Lichen Planus and Dyslipidemia: A Systematic Review and Meta-Analysis of Observational Studies
February 2016
in “
International Journal of Dermatology
”
TLDR People with lichen planus are more likely to have dyslipidemia, especially higher triglyceride levels.
In 2016, a meta-analysis of seven studies with a total of 5242 subjects found that patients with lichen planus (LP) had a significantly higher likelihood of having dyslipidemia, with a pooled odds ratio of 1.74. Specifically, LP was associated with elevated triglyceride levels, but no significant association was found with LDL-C, HDL-C, or total cholesterol levels. Despite the study's limitations, such as heterogeneity among studies and potential publication bias, the findings suggest that LP patients may have an increased risk of dyslipidemia and could benefit from screening and management for this condition. The study calls for further research to confirm these findings and to explore the long-term cardiovascular risks associated with dyslipidemia in LP patients.
