Lipid Profile and Metabolic Syndrome Status in Patients with Oral Lichen Planus, Oral Lichenoid Reaction, and Healthy Individuals Attending a Dental College in Northern India: A Descriptive Study

January 2014 in “ Journal of Clinical and Diagnostic Research ”

B Krishnamoorthy, GN Suma, Komali Garlapati

oral lichen planus oral lichenoid reactions serum cholesterol LDL-C serum triglyceride VLDL HDL-C BMI obesity chronic inflammation dyslipidemia cardiovascular disease low-density lipoprotein cholesterol very low-density lipoprotein high-density lipoprotein cholesterol body mass index

Studysummary This study found that patients with oral lichen planus and oral lichenoid reactions have higher levels of serum cholesterol and LDL-C than healthy individuals, suggesting a potential elevated risk for cardiovascular disease. Our plain-language summary of this paper — not a Tressless recommendation.

The 2014 study evaluated the lipid profiles and metabolic syndrome status in 32 adults, with 18 patients having oral lichen planus (OLP) or oral lichenoid reactions (OLR) and 14 healthy controls. It found that patients with OLP and OLR had higher serum cholesterol and LDL-C levels than healthy individuals. OLP patients also had significantly higher serum triglyceride and VLDL levels, and lower HDL-C levels compared to OLR patients. Additionally, a higher percentage of OLP and OLR patients had high BMI indicative of obesity. The study suggested a potential link between chronic inflammation and dyslipidemia, which could increase cardiovascular disease risk, and highlighted the need for further research on lipid levels in OLR patients.

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