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      learn Spironolactone

      powerful topical and oral anti-androgen used mostly by women

      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

    Research

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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 6 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community One year of progress (Fin, 1mg)

      in Is this regrowth?  281 upvotes 1 month ago
      The user started finasteride (1mg) a year ago for hair thinning, experiencing stabilization but not significant regrowth. Suggestions included adding minoxidil, microneedling, and considering a hair transplant for improved results.

      community Oral minoxidil and oral finasteride progress

      in Progress Pictures  59 upvotes 1 month ago
      The user has been using oral finasteride 1mg and oral minoxidil 2.5mg daily since late 2024 and reports positive progress in hair growth without side effects, though some unwanted hair growth on hands and arms. The user is 26 years old and started losing hair around age 20 or 21.

      community Being Safe on Oral Minoxidil: tl;dr on the literature.

      in Research/Science  49 upvotes 1 month ago
      Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.