A Study on the Relationship Between Androgenetic Alopecia and Cardiovascular Risk Using High Sensitivity C-Reactive Protein and Galectin-3 in Men With Early Onset Baldness

December 2021 in “ Biomarkers ”

Mehmet Sözen, Suleyman Baldane, Sedat Abusoglu, Levent Kebapcilar, Aysegul Kebapcilar, Fatma Tunçez Akyürek, Ali Ünlü, Suleyman Hilmi Ipekci

androgenetic alopecia AGA high sensitivity C-reactive protein hsCRP galectin-3 Hamilton-Norwood scale triglyceride levels fasting blood glucose levels BMI waist circumference male pattern baldness baldness scale

TLDR Men with early baldness have similar heart risk factors as others, but certain proteins are linked to higher heart disease risk.

This study investigated the cardiovascular and metabolic effects in men with early-onset androgenetic alopecia (AGA) by comparing 41 men with AGA to 40 healthy individuals. The research found that 24-hour ambulatory blood pressure, high sensitivity C-reactive protein (hsCRP), and galectin-3 levels were similar between the two groups. However, in individuals with AGA, there was a positive correlation between the Hamilton-Norwood scale grade and factors such as age, BMI, triglyceride levels, and fasting blood glucose levels. Additionally, hsCRP and galectin-3 were associated with cardiovascular risk factors like BMI and waist circumference. The study concludes that while AGA patients are similar to the normal population regarding insulin resistance or metabolic syndrome components, hsCRP and galectin-3 are linked to cardiovascular disease risk factors in those with AGA.

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