Increased DHEAS and Decreased Total Testosterone Serum Levels in a Subset of Men with Early-Onset Androgenetic Alopecia: Does a Male PCOS-Equivalent Exist?

    Rossella Cannarella, Rosita A. Condorelli, Federica Dall'Oglio, Sandro La Vignera, Laura M. Mongioì, Giuseppe Micali, Aldo E. Calogero
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    TLDR Some men with early hair loss may have a male version of PCOS, affecting hormones and increasing health risks.
    A study from 3 years ago suggests that some men with early-onset androgenetic alopecia (AGA) may have a male equivalent of polycystic ovary syndrome (PCOS), with increased levels of DHEAS and decreased levels of total testosterone. This hormonal profile is similar to that seen in women with PCOS and may increase the risk of metabolic and cardiovascular diseases. Further research is needed to confirm the existence of a male PCOS-equivalent and its implications for managing AGA.
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