The Post-Finasteride Syndrome: Possible Etiological Mechanisms and Symptoms

September 2023 in “ International journal of impotence research ”

Herman H. J. Leliefeld, F.M.J. Debruyne, Yacov Reisman

post-finasteride syndrome PFS finasteride androgenetic alopecia benign prostatic hyperplasia erectile dysfunction reduced libido depression anxiety Propecia

Studysummary The authors concluded that finasteride and dutasteride might have serious side effects, including persistent sexual dysfunction for some, necessitating further research and vigilant risk-benefit analysis. Our plain-language summary of this paper — not a Tressless recommendation.

The document reviews post-finasteride syndrome (PFS), which includes persistent sexual, neurological, and physical side effects after stopping finasteride, used for androgenetic alopecia and benign prostatic hyperplasia. It highlights studies documenting adverse effects like erectile dysfunction, reduced libido, depression, and anxiety. The review calls for more research to understand PFS mechanisms and develop effective treatments.

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