Rare and Common Genetic Determinants of Metabolic Individuality and Their Effects on Human Health

    November 2022 in “ Nature Medicine ”
    Praveen Surendran, Isobel D. Stewart, Victoria P W Au Yeung … Claudia Langenberg
    Studysummary This study identified thousands of variant-metabolite associations in the human plasma metabolome, offering insights into the genetic bases of metabolism and potential adverse drug effects.
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    Research cited in this study 4

    1. Investigation of Suicidality and Psychological Adverse Events in Patients Treated With Finasteride JAMA Dermatology · 2020
    2. Dissection of Genetic Variation and Evidence for Pleiotropy in Male Pattern Baldness Nature Communications · 2018
    3. Adverse Effects of 5α-Reductase Inhibitors: What Do We Know, Don't Know, and Need to Know? Reviews in Endocrine and Metabolic Disorders · 2015
    4. Plasma Androsterone/Epiandrosterone Sulfates as Markers of 5α-Reductase Activity: Effect of Finasteride in Normal Men Steroids · 1997