Diagnostic Criteria for Enduring Sexual Dysfunction After Treatment With Antidepressants, Finasteride, and Isotretinoin

    October 2021 in “ The international journal of risk and safety in medicine ”
    David Healy, Audrey S. Bahrick, Maarten Bak, Angelo Barbato, Rocco Salvatore Calabrò, Barbara Chubak, Fiammetta Cosci, Antonei B. Csoka, Barbara D'Avanzo, Silvia Diviccaro, Silvia Giatti, Irwin Goldstein, Heiko Graf, Wayne J.G. Hellstrom, Michael S. Irwig, Emmanuele A. Jannini, Paddy K.C. Janssen, Mohit Khera, Manoj Therayil Kumar, Joanna Le Noury, Michał Lew-Starowicz, David Edmund Johannes Linden, C. Lüning, Dee Mangin, Roberto Cosimo Melcangi, Omar Walid Muquebil Ali Al Shaban Rodríguez, Jalesh N. Panicker, Arianna Patacchini, Amy M. Pearlman, Caroline F. Pukall, Sanjana Raj, Yacov Reisman, Rachel Rubin, Rudy Schreiber, Stuart Shipko, Barbora Vašečková, Ahad Waraich
    TLDR The document sets criteria for diagnosing long-term sexual dysfunctions caused by certain medications.
    The document establishes diagnostic criteria for enduring sexual dysfunctions following the use of antidepressants, finasteride, and isotretinoin, including conditions like post-SSRI sexual dysfunction (PSSD), post-finasteride syndrome (PFS), and post-retinoid sexual dysfunction (PRSD). Common symptoms are decreased genital sensation, reduced sexual desire, and erectile dysfunction. The criteria were developed from two large case series and refined by a multidisciplinary panel to improve diagnosis and research, acknowledging potential future adjustments. The document also introduces Post-SSRI asexuality, linked to early SSRI exposure, and notes that similar dysfunctions may arise from other drugs like antipsychotics and NOACs.
    Discuss this study in the Community →

    Research cited in this study

    7 / 7 results

    Related Community Posts Join

    6 / 1000+ results

      community I’m really tired of using minoxidil

      in Minoxidil  42 upvotes 1 year ago
      The user is frustrated with minoxidil's lack of results and is considering alternatives like oral minoxidil or finasteride despite concerns about side effects. Other suggestions include consulting a doctor, adjusting dosages, or considering a hair transplant.

      community Seborrheic dermatitis - can it cause long-term shedding (or telogen effluvium)?

      in Advice  6 upvotes 4 years ago
      A user is experiencing significant hair loss and scalp issues despite using Minoxidil, finasteride, and RU58841 since 2017. They switched to oral Minoxidil and are now on isotretinoin and topical corticosteroids for seborrheic dermatitis but continue to lose hair and seek advice on whether inflammation or treatment changes are the cause.

      community No, Finasteride as a treatment for MPB was not an "accident"

      in Research/Science  105 upvotes 3 years ago
      Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.

      community I talked to urologist about Finasteride and just wanted to share what he said

      in Finasteride  234 upvotes 7 years ago
      The effects of Finasteride, a drug used to treat hair loss, prostate problems and other conditions. The post by iaskedadoctor describes the conversations they had with a Urologist about the effects of the drug on DHT levels throughout the body, how lower doses are beneficial in reducing side effects, how erectile dysfunction can be psychological as well as physiological, how morning erections are not necessarily important, and how persistent side effects appear to be rare. People also shared their experiences with taking Finasteride for hair loss, including potential side effects such as reduced ejaculate force and development of man boobs.

    Similar Research

    5 / 1000+ results