The Effect of the Aqueous Extract of Bidens Pilosa L. on Androgen Deficiency Dry Eye in Rats

    January 2016 in “ Cellular Physiology and Biochemistry ”
    Chuanwei Zhang, Kai Li, Zichao Yang, Yuliang Wang, Haipeng Si
    TLDR Bidens pilosa L. extract effectively treats androgen deficiency dry eye in rats.
    The study examined the effects of Bidens Pilosa L. (Bp) extract on androgen deficiency dry eye in rats, a condition marked by reduced tear production and inflammation. Conducted on 24 rats, the research found that finasteride induced dry eye symptoms, but Bp extract significantly improved tear secretion, tear film stability, and reduced inflammation and corneal damage. The extract's anti-inflammatory properties, including flavonoids, were suggested to have androgen-like effects, potentially beneficial for treating dry eye, particularly in females. The study concluded that Bp could alleviate mild dry eye symptoms by enhancing tear production and reducing inflammation, though further research was needed to confirm its effectiveness in humans.
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