Hair Follicle Stem Cells Promote Epidermal Regeneration Under Expanded Condition

    February 2024 in “ Frontiers in physiology ”
    Yu Zhang, Jian Cui, Zheng-Qiang Cang … Li Yang
    Studysummary This study examines the role of hair follicle stem cells in epidermal regeneration during skin soft tissue expansion, proposing a potential method for their cellular and molecular regulation.
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    Research cited in this study 46

    1. Deciphering the Molecular Mechanisms of Stem Cell Dynamics in Hair Follicle Regeneration 2024
    2. Biological and Mechanical Influence of Three-Dimensional Microenvironment Formed in Microwell on Multicellular Spheroids Composed of Heterogeneous Hair Follicle Stem Cells Scientific reports · 2023
    3. The Roles of WNT Signaling Pathways in Skin Development and Mechanical-Stretch-Induced Skin Regeneration Biomolecules · 2023
    4. Status of Research on the Development and Regeneration of Hair Follicles International Journal of Medical Sciences · 2023
    5. Single Cell Analysis of Transcriptome and Open Chromatin Reveals the Dynamics of Hair Follicle Stem Cell Aging Frontiers in Aging · 2023
    6. New Insights Into Inflammatory Memory of Epidermal Stem Cells Frontiers in immunology · 2023
    7. Single-Cell Profiling Reveals a Potent Role of Quercetin in Promoting Hair Regeneration Protein & Cell · 2022
    8. Plasticity of Epithelial Cells During Skin Wound Healing Cold Spring Harbor Perspectives in Biology · 2022
    9. Mesenchymal Stem Cells From Mouse Hair Follicles Reduce Hypertrophic Scarring in a Murine Wound Healing Model Stem cell reviews and reports · 2022
    10. Building and Maintaining the Skin Cold Spring Harbor Perspectives in Biology · 2021
    11. A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells Stem Cell Research & Therapy · 2021
    12. Mechanical and Immunological Regulation in Wound Healing and Skin Reconstruction International Journal of Molecular Sciences · 2021
    13. Functional Hair Follicle Regeneration: An Updated Review Signal Transduction and Targeted Therapy · 2021
    14. Hair Follicle Bulge-Derived Stem Cells Promote Tissue Regeneration During Skin Expansion Biomedicine & Pharmacotherapy · 2020
    15. Progress in Studies of Epidermal Stem Cells and Their Application in Skin Tissue Engineering Stem Cell Research & Therapy · 2020
    16. Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells Cell · 2020
    17. Multimodal Imaging of Hair Follicle Bulge-Derived Stem Cells in a Mouse Model of Traumatic Brain Injury Cell & tissue research/Cell and tissue research · 2020
    18. Effects of Hair Follicle Stem Cells on Partial-Thickness Burn Wound Healing and Tensile Strength Iranian Biomedical Journal · 2019
    19. Hes1 Regulates Anagen Initiation and Hair Follicle Regeneration Through Modulation of Hedgehog Signaling Stem Cells · 2019
    20. Stimulation of Hair Growth by Small Molecules That Activate Autophagy Cell reports · 2019
    21. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019
    22. Mechanical Stretch Induces Hair Regeneration Through the Alternative Activation of Macrophages Nature Communications · 2019
    23. Macrophages Are Necessary for Skin Regeneration During Tissue Expansion Journal of Translational Medicine · 2019
    24. Eclipta Prostrata Promotes the Induction of Anagen, Sustains the Anagen Phase Through Regulation of FGF-7 and FGF-5 Pharmaceutical Biology · 2019
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    26. Hedgehog Stimulates Hair Follicle Neogenesis by Creating Inductive Dermis During Murine Skin Wound Healing Nature Communications · 2018
    27. Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations During Wound Healing Cell Reports · 2018
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    29. Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells Stem cells · 2017
    30. Activation of TRPV3 Regulates Inflammatory Actions of Human Epidermal Keratinocytes Journal of Investigative Dermatology · 2017
    31. Hair-Follicle Transplant Into Chronic Ulcers: A New Graft Concept Actas dermo-sifiliográficas/Actas dermo-sifiliográficas · 2017
    32. VEGF165 Induces Differentiation of Hair Follicle Stem Cells Into Endothelial Cells and Plays a Role in In Vivo Angiogenesis Journal of Cellular and Molecular Medicine · 2017
    33. Msi2 Maintains Quiescent State of Hair Follicle Stem Cells by Directly Repressing the Hedgehog Signaling Pathway Journal of Investigative Dermatology · 2017
    34. Epidermal Growth Factor Promotes Mesenchymal Stem Cell-Mediated Wound Healing and Hair Follicle Regeneration PubMed · 2017
    35. DNA Damage-Inducible Transcript 4 Is an Innate Surveillant of Hair Follicular Stress in Vitamin D Receptor Knockout Mice and a Regulator of Wound Re-Epithelialization International journal of molecular sciences · 2016
    36. Regeneration of Hair and Other Skin Appendages: A Microenvironment-Centric View Wound Repair and Regeneration · 2016
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    38. BMP-FGF Signaling Axis Mediates Wnt-Induced Epidermal Stratification in Developing Mammalian Skin PLoS Genetics · 2014
    39. Emerging Interactions Between Skin Stem Cells and Their Niches Nature Medicine · 2014
    40. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014
    41. Differentiation of Human Hair Follicle Stem Cells Into Endothelial Cells Induced by Vascular Endothelial and Basic Fibroblast Growth Factors Molecular Medicine Reports · 2013
    42. Spatial Organization Within a Niche as a Determinant of Stem-Cell Fate Nature · 2013
    43. Hairless Down-Regulates Expression of Msx2 and Its Related Target Genes in Hair Follicles Journal of dermatological science · 2013
    44. Induced Pluripotent Stem Cells From Human Hair Follicle Mesenchymal Stem Cells Stem Cell Reviews and Reports · 2012
    45. An Extended Epidermal Response Heals Cutaneous Wounds in the Absence of a Hair Follicle Stem Cell Contribution ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2007
    46. Implanted Hair Follicle Stem Cells Form Schwann Cells That Support Repair of Severed Peripheral Nerves Proceedings of the National Academy of Sciences · 2005

    Related research 5

    1. Dermal Fibroblast Expression of LEF1 Is Critical to Normal Skin and Hair Development and Regenerative Wound Healing in Mice Journal of Investigative Dermatology · 2022
    2. Hair Follicle Bulge-Derived Stem Cells Promote Tissue Regeneration During Skin Expansion Biomedicine & Pharmacotherapy · 2020
    3. Promoting Effect of Hair Follicle Stem Cells in the Wound Healing of Skin Chin J Cell Stem Cell (Electronic Edition) · 2017
    4. The Effect of Flavonoids on Regenerated Hair Follicles with Pigmentation Journal of Dermatological Science · 2017
    5. Understanding the Functional Contribution of Dermal Stem Cells to Hair Follicle Regeneration and Skin Wound Healing 2017