19 citations
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February 2022 in “Journal of Investigative Dermatology” Mechanical stretching can improve or hinder skin regeneration depending on duration.
43 citations
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December 2013 in “Stem Cells” Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.
1 citations
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November 2022 in “Pharmaceutical research” In this study, the authors found that applying hypobaric pressure to the skin significantly increases the transdermal permeation of large molecules by enhancing diffusion, despite the associated skin stretching and hair follicle enlargement not fully explaining this effect.
October 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study found that applying the right mechanical stretch to skin can activate hair stem cells and promote hair regeneration through a pathway involving WNT, BMP-2, and M2 macrophages.
July 2024 in “Journal of Investigative Dermatology” Mechanical tension worsens keloid scars by activating inflammation and fibrosis pathways.