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    GlossaryCollagen Architecture

    specific arrangement of collagen fibers within tissues

    Collagen architecture refers to the specific arrangement and organization of collagen fibers within tissues. This structure is crucial because it influences the mechanical properties and function of the tissue, such as skin elasticity and strength. In the context of hair and alopecia, changes in collagen architecture can affect the health of hair follicles and potentially contribute to hair loss.

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      community Verteporfin and Microneedling

      in Treatments 5 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community oral minoxidil collagen contradiction

      in Minoxidil  13 upvotes 5 months ago
      The conversation discusses concerns about oral minoxidil potentially aging the face by affecting collagen, questioning its systemic effects. The user has successfully used topical minoxidil for years and is hesitant to switch to oral minoxidil.