The Role of Vitamin D Receptor Signaling in Hair Follicle Health and Alopecia: Current Understanding and Therapeutic Implications

    Liancheng Guan, Fan Yang, M Li, Yujia Chen, Zexin Zhao, Hongxia Li, Deping Luo, Qian Li, Yunzhi Chen
    Vitamin D receptor (VDR) signaling is essential for hair follicle health and offers a potential therapeutic target for alopecia. This review delves into the molecular mechanisms of VDR in hair follicle development and maintenance, highlighting its role in gene regulation and hair follicle homeostasis. It discusses the impact of VDR genetic polymorphisms on treatment responses, paving the way for personalized therapies. Current and emerging therapeutic strategies, including vitamin D supplementation and targeted delivery systems, are explored, alongside the challenges of improving delivery systems and identifying reliable biomarkers. The review emphasizes the promise of VDR-targeted treatments in managing hair disorders and the need for ongoing research.
    Discuss this study in the Community →

    Research cited in this study

    56 / 56 results

    Related Community Posts Join

    6 / 1000+ results

    Similar Research

    6 / 1000+ results