Histological Characteristics of Hair Follicles at Different Hair Cycle and In Vitro Modeling of Hair Follicle-Associated Cells of Yak (Bos Grunniens)

    November 2023 in “ Frontiers in veterinary science
    Bo Liao, Yan Cui, Sijiu Yu, Junlin He, Xue Yang, Shengnan Zou, Sijie Li, Pengfei Zhao, Hui Xu, Min Long, Xiaoyan Wang
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    TLDR The study provides insights into hair growth mechanisms in yaks.
    This study on yaks (Bos grunniens) aimed to understand hair follicle development and cyclic growth in extreme plateau environments. Researchers examined skin tissue structures during different hair follicle cycles and established in vitro models of hair follicle-associated cells, including dermal papilla cells (DPCs), preadipocytes, and fibroblasts. They optimized DPC culture techniques and improved preadipocyte differentiation into mature adipocytes. The findings provide valuable insights into hair growth mechanisms and contribute to hair follicle biology and regenerative medicine strategies.
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