Role of the Vitamin D Receptor in Hair Follicle Biology
January 2007
in “
The Journal of Steroid Biochemistry and Molecular Biology
”
Research cited in this study
8 / 8 resultsresearch Hair Follicle Expression of 1,25-Dihydroxyvitamin D3 Receptors During the Murine Hair Cycle
This study investigated the expression of vitamin D receptors (VDR) in hair follicles during the murine hair cycle, using C57 BL-6 mice. VDR expression was detected in both outer root sheath keratinocytes and dermal papilla cells, with stronger immunoreactivity observed during the anagen IV-VI and catagen phases compared to telogen and anagen I-III. These findings suggested that VDR expression varied with the hair cycle, indicating a potential role for 1,25-dihydroxyvitamin D3 in hair follicle biology and suggesting that certain follicular cell populations might have hair cycle-dependent sensitivity to this hormone.
research Ligand-Independent Actions of the Vitamin D Receptor Maintain Hair Follicle Homeostasis
research Deletion of DNA Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D
Removing part of the vitamin D receptor stops vitamin D from working properly.
research Lack of the Vitamin D Receptor Is Associated with Reduced Epidermal Differentiation and Hair Follicle Growth
Vitamin D Receptor is crucial for normal skin and hair growth.
research Targeting Expression of the Human Vitamin D Receptor to the Keratinocytes of Vitamin D Receptor Null Mice Prevents Alopecia
research Metabolic and cellular analysis of alopecia in vitamin D receptor knockout mice
research Evaluation of Keratinocyte Proliferation and Differentiation in Vitamin D Receptor Knockout Mice*
research Alopecia Universalis Associated with a Mutation in the Human hairless Gene
A mutation in the human hairless gene causes alopecia universalis.
Related Research
2 / 2 resultsresearch Contrasting Localization of c-Myc with Other Myc Superfamily Transcription Factors in the Human Hair Follicle and During the Hair Growth Cycle
Different Myc family proteins are located in various parts of the hair follicle and may affect stem cell behavior.
research Expression of E6 and E7 papillomavirus oncogenes in the outer root sheath of hair follicles extends the growth phase and bypasses resting at telogen.
E6/E7 oncogenes in hair follicles cause continuous hair growth by skipping the resting phase.