Androgenetic Alopecia in Women: A Narrative Review of Pathophysiology, Clinical Evaluation, and Treatments

    Caitlin A. Kearney, Anna L. Brinks, Carli D. Needle, D. Maas, Archie Spindler, Christina Coric, Liezel A. Gener-Pangilinan, M A Lasheras-Perez, Jerry Shapiro, Kristen I. Lo Sicco
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    TLDR Spironolactone is effective for treating female hair loss, with new treatments like clascoterone showing promise.
    The narrative review on androgenetic alopecia in women explores the condition's pathophysiology, clinical evaluation, and treatment options. It highlights spironolactone as a common and effective treatment, while also discussing the use of finasteride and dutasteride, though their effectiveness in postmenopausal women is uncertain. The review introduces clascoterone, a new topical treatment, and notes the promising results of combining low-dose oral minoxidil with spironolactone. The importance of personalized treatment plans and further research to enhance therapeutic strategies for women with androgenetic alopecia is emphasized.
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