Guidelines of Care for the Management of Acne Vulgaris

    January 2024 in “ Journal of the American Academy of Dermatology ”
    Rachel V. Reynolds, Howa Yeung, Carol E. Cheng … John S. Barbieri
    Studysummary This study provided 18 evidence-based recommendations for managing acne vulgaris, strongly endorsing treatments like benzoyl peroxide, topical retinoids, and oral isotretinoin for severe cases, and issued conditional recommendations for therapies like salicylic acid and spironolactone, while offering good practice statements on combining treatment methods.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 13

    1. Association of Spironolactone Use With Risk of Cancer: A Systematic Review and Meta-Analysis JAMA Dermatology · 2022
    2. Consensus on the Use of Oral Isotretinoin in Dermatology - Brazilian Society of Dermatology Anais Brasileiros de Dermatologia · 2020
    3. Oral Spironolactone for Acne Vulgaris in Adult Females: A Hybrid Systematic Review American Journal of Clinical Dermatology · 2017
    4. Spironolactone for the Treatment of Acne: A 4-Year Retrospective Study Dermatology · 2017
    5. Intralesional Triamcinolone for Flares of Hidradenitis Suppurativa: A Case Series Journal of the American Academy of Dermatology · 2016
    6. Safety of Dermatologic Medications in Pregnancy and Lactation Journal of The American Academy of Dermatology · 2014
    7. Safety of Dermatologic Medications in Pregnancy and Lactation Journal of The American Academy of Dermatology · 2014
    8. Hormonal Therapy for Acne: Why Not as First Line Therapy? Facts and Controversies Clinics in Dermatology · 2009
    9. Efficacy of an Oral Contraceptive Containing EE 0.03 mg and CMA 2 mg (Belara) in Moderate Acne Resolution: A Randomized, Double-Blind, Placebo-Controlled Phase III Trial Contraception · 2009
    10. Inhibition of Skin 5α-Reductase by Oral Contraceptive Progestins In Vitro Gynecological Endocrinology · 2000
    11. Androgens Affect the Activity of Human Sebocytes in Culture Depending on the Localization of the Sebaceous Glands, and Their Effect Is Antagonized by Spironolactone Skin Pharmacology and Physiology · 1994
    12. The Effect of Spironolactone on Genital Skin 5α-Reductase Activity Journal of steroid biochemistry/Journal of Steroid Biochemistry · 1985
    13. Interaction of Spironolactone with Rat Skin Androgen Receptor Canadian journal of biochemistry · 1979