Recent Therapeutic Developments for Acne

    February 2013 in “ Expert Review of Dermatology ”
    Anja Thielitz, Harald Gollnick
    Image of study
    TLDR New acne treatments include combination creams, advanced retinoids, and light therapies, focusing on safety and patient adherence.
    The 2013 document reviews the state of acne treatment, emphasizing the chronic inflammatory nature of the condition and the influence of genetic, microbial, and environmental factors. It highlights the use of topical fixed combinations, such as benzoyl peroxide with adapalene or clindamycin, to enhance efficacy and prevent bacterial resistance. The European S3 guidelines are noted for providing severity-adjusted treatment recommendations. Topical retinoids are underscored for their anti-inflammatory properties and role in maintenance therapy. New delivery systems for tretinoin and the efficacy of adapalene and tazarotene are discussed, as well as the importance of combination therapies. Oral antibiotics, hormonal therapies, and oral isotretinoin are reviewed for moderate-to-severe acne, with a caution on the side effects of isotretinoin and minocycline. Adjunctive treatments like light and laser therapies are mentioned, with a focus on patient adherence to improve treatment outcomes. The document also explores emerging therapies and the need for more evidence to support their use, concluding that acne management should be multifactorial, safe, and effective, with a focus on patient adherence.
    Discuss this study in the Community →

    Research cited in this study

    4 / 4 results

    Related Community Posts Join

    6 / 24 results

      community Yeah, it’s working 👍🏻 Nov 2023 to March 2024

      in Progress Pictures  63 upvotes 10 months ago
      Animajax, who started off completely bald, has seen hair regrowth using finasteride 1.25mg, oral minoxidil 2.5mg, occasional topical minoxidil, dermastamping, benzoyl peroxide, and tretinoin. They recently added nizoral and plan to switch to a topical solution combining minoxidil and dutasteride.
      [object Object]

      community I feel like my progress sucks. About 6 Months

      in Progress Pictures  11 upvotes 10 months ago
      A user is disappointed with their 6-month hair loss treatment progress, using 1.25mg oral finasteride daily, 2.5mg oral minoxidil daily, topical minoxidil, derma stamping, vitamin D, caffeine, benzoyl peroxide wash, and tretinoin. Replies suggest the results are good, especially considering the late start of treatment, and encourage continued use for better outcomes.

      community Finally Scalp Folliculitis-Free after 2 Decades of Suffering

      in Treatment  61 upvotes 2 months ago
      A 37-year-old male resolved scalp folliculitis by adopting a low-histamine diet and taking Vitamin A, Zinc, and Fish Oil, leading to better skin health and thicker hair. He warns about the potential toxicity of excessive Vitamin A intake.

      community The Truth About DUPA and Retrograde: My Research Summary

      in Research/Science  19 upvotes 5 months ago
      The conversation discusses the importance of scalp biopsies for diagnosing hair loss conditions like DUPA and Retrograde, which may not be just AGA. It emphasizes that treatments like finasteride and dutasteride may not work if the condition is autoimmune.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 4 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

    Similar Research

    5 / 667 results
      Acne

      research Acne

      231 citations, April 2005 in “The New England Journal of Medicine”
      Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.
      Management of Acne

      research Management of Acne

      78 citations, February 2011 in “Canadian Medical Association Journal”
      Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.
      [object Object]
      Side Effects of Common Acne Treatments

      research Side Effects of Common Acne Treatments

      38 citations, November 2012 in “Expert Opinion on Drug Safety”
      Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.