Oral Spironolactone for Acne Vulgaris in Adult Females: A Hybrid Systematic Review

    Alison Layton, E. Anne Eady, Heather Whitehouse … Esther J van Zuuren
    Studysummary This systematic review concluded that the support for using spironolactone at commonly prescribed doses is based on evidence of limited quality.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 22

    1. Adult Female Acne and Associated Risk Factors: Results of a Multicenter Case-Control Study in Italy Journal of The American Academy of Dermatology · 2016
    2. Status Report From The American Acne & Rosacea Society On Medical Management Of Acne In Adult Women, Part 1: Overview, Clinical Characteristics, And Laboratory Evaluation PubMed · 2015
    3. Evidence-Based Approach to Cutaneous Hyperandrogenism in Women Journal of The American Academy of Dermatology · 2015
    4. Is Hormonal Treatment Still an Option in Acne Today? British Journal of Dermatology · 2015
    5. Contraceptive Use in Acne Clinics in Dermatology · 2014
    6. Androgenic Hormone Profile of Adult Women with Acne Dermatology · 2013
    7. A Comparative Study of Diane-35 Plus Spironolactone and Diane-35 Plus Finasteride in Cases of Hirsutism and Acne International Journal of Endocrinology and Metabolism · 2009
    8. Spironolactone Versus Placebo or in Combination with Steroids for Hirsutism and/or Acne Cochrane library · 2009
    9. Androgen Dependence of Hirsutism, Acne, and Alopecia in Women Medicine · 2009
    10. Effect of Finasteride 5 mg (Proscar) on Acne and Alopecia in Female Patients with Normal Serum Levels of Free Testosterone Gynecological Endocrinology · 2007
    11. Androgen Excess in Women: Experience with Over 1000 Consecutive Patients The Journal of Clinical Endocrinology and Metabolism · 2004
    12. Effects of a Phasic Oral Contraceptive Containing Desogestrel on Facial Seborrhea and Acne Contraception · 2003
    13. A Comparison of the Relative Efficacy of Antiandrogens for the Treatment of Acne in Hyperandrogenic Women Clinical Endocrinology · 2002
    14. The Effect of Two Combined Oral Contraceptives Containing Either Drospirenone or Cyproterone Acetate on Acne and Seborrhea PubMed · 2002
    15. Other Antiandrogens: Alternative Treatments for Acne and Hirsutism Dermatology · 1998
    16. Comparison of Flutamide and Spironolactone in the Treatment of Hirsutism: A Randomized Controlled Trial Fertility and Sterility · 1994
    17. Spironolactone Therapeutic Effect in the Hyperandrogenism Syndrome Problemy e̊ndokrinologii · 1993
    18. Ketoconazole Therapy for Women with Acne and/or Hirsutism ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 1990
    19. Low-Dose Spironolactone in the Treatment of Female Hirsutism PubMed · 1987
    20. Spironolactone Therapy for Hyperandrogenic Anovulatory Women: Clinical and Endocrinological Study PubMed · 1986
    21. Oral Spironolactone Therapy for Female Patients with Acne, Hirsutism, or Androgenic Alopecia British Journal of Dermatology · 1985
    22. Treatment of Hirsutism and Acne in Women With Two Combinations of Cyproterone Acetate and Ethinylestradiol PubMed · 1976

    Related research 2

    1. Spironolactone for the Treatment of Acne: A 4-Year Retrospective Study Dermatology · 2017
    2. Lack of Effect of Spironolactone on Hair Shaft Diameter in Hirsute Females Postgraduate medical journal · 1989