Treatment of Hirsutism and Acne in Women With Two Combinations of Cyproterone Acetate and Ethinylestradiol

December 1976 in “ PubMed ”

C Cremoncini, E Vignati, A. Libroia

cyproterone acetate ethinylestradiol hirsutism acne SH 8.1041 SH B209AB

TLDR Cyproterone acetate and ethinylestradiol effectively reduce hirsutism and acne in women.

The study involved 175 women with hirsutism and acne, treated with two combinations of cyproterone acetate and ethinylestradiol (SH 8.1041 and SH B209AB). SH 8.1041 showed significant improvement in most patients, while SH B209AB was used for maintenance therapy and initial treatment for milder acne. Hirsutism reduction was noticeable after the fourth cycle, and acne improved after the first month. Both treatments were well-tolerated, though some patients on SH 8.1041 experienced mild side effects like transient frigidity, depression, breast discomfort, and nausea.

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research The Effect of Cyproterone Acetate and Ethinylestradiol Combination on Hyperandrogenic and Other Symptoms in PCOS

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The hormonal contraceptive combination effectively reduces androgen excess and improves PCOS symptoms like acne, hair loss, and menstrual issues.

research Treatment of Hirsutism and Acne in Women With Two Combinations of Cyproterone Acetate and Ethinylestradiol

42 citations , December 1976 in “PubMed”

Cyproterone acetate and ethinylestradiol effectively reduce hirsutism and acne in women.