Efficacy And Safety Of Dutasteride In The Treatment Of Alopecia: A Comprehensive Review

    January 2025 in “ Expert Opinion on Pharmacotherapy
    Aditya K. Gupta, Mesbah Talukder
    Image of study
    TLDR Dutasteride is more effective than finasteride for hair loss but may affect male fertility and should be used cautiously.
    The review discusses the efficacy and safety of dutasteride in treating androgenetic alopecia (AGA), highlighting that it is more effective than finasteride and minoxidil for male AGA. Both dutasteride and finasteride are 5-alpha reductase inhibitors with similar safety profiles. The review suggests that topical minoxidil and oral finasteride should be first-line treatments for AGA, with oral dutasteride considered off-label for males and post-menopausal females if these are ineffective. However, dutasteride may affect male fertility by reducing sperm count and motility, and men whose partners are pregnant should avoid it. Dutasteride can remain in the bloodstream for up to 6 months after stopping, affecting blood donation eligibility. The authors declare no conflicts of interest, and the paper was not funded.
    Discuss this study in the Community →

    Research cited in this study

    40 / 40 results

    Related Community Posts Join

    6 / 1000+ results

    Related Research

    3 / 3 results