The Relative Effect of Monotherapy with 5-Alpha Reductase Inhibitors and Minoxidil for Female Pattern Hair Loss: A Network Meta-Analysis Study

    June 2023 in “ Journal of Cosmetic Dermatology ”
    Aditya K. Gupta, Tong Wang, Mary A Bamimore, Milton Talukder
    Studysummary This research highlights that while minoxidil and 5-alpha reductase inhibitors are commonly used for treating pattern hair loss, there is limited evidence supporting their relative effectiveness in women compared to men.
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    Research cited in this study 13

    1. Efficacy and Safety of 5% Minoxidil Alone, Minoxidil Plus Oral Spironolactone, and Minoxidil Plus Microneedling on Female Pattern Hair Loss: A Prospective, Single-Center, Parallel-Group, Evaluator-Blinded, Randomized Trial Frontiers in Medicine · 2022
    2. Relative Efficacy of Minoxidil and the 5-Alpha Reductase Inhibitors in Androgenetic Alopecia Treatment of Male Patients JAMA Dermatology · 2022
    3. Randomized Clinical Trial of Low-Dose Oral Minoxidil for the Treatment of Female Pattern Hair Loss: 0.25 mg Versus 1 mg Journal of The American Academy of Dermatology · 2022
    4. A Randomized Clinical Trial on Therapeutic Effects of 0.25 mg Oral Minoxidil Tablets on Treatment of Female Pattern Hair Loss Dermatologic Therapy · 2021
    5. Male and Female Pattern Hair Loss: Treatable and Worth Treating Cleveland Clinic Journal of Medicine · 2021
    6. Comparison of Low-Level Light Therapy and Combination Therapy of 5% Minoxidil in the Treatment of Female Pattern Hair Loss Lasers in Medical Science · 2020
    7. Evaluation of the Efficacy and Safety of Cow Placenta Extract Lotion Versus Minoxidil 2% in the Treatment of Female Pattern Androgenetic Alopecia International Journal of Women's Dermatology · 2020
    8. Accelerated Hair Growth by Combining Thread Monofilament and Minoxidil in Female Androgenetic Alopecia Journal of Cosmetic Dermatology · 2019
    9. Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study American Journal of Clinical Dermatology · 2018
    10. Efficacy of Finasteride 1.25 mg on Female Pattern Hair Loss: Pilot Study Annals of Dermatology · 2012
    11. 5 mg/Day Finasteride Treatment for Normoandrogenic Asian Women with Female Pattern Hair Loss Journal of The European Academy of Dermatology and Venereology · 2010
    12. Comparison of the Efficacy and Safety of Topical Minoxidil and Topical Alfatradiol in the Treatment of Androgenetic Alopecia in Women Journal der Deutschen Dermatologischen Gesellschaft · 2007
    13. Lack of Efficacy of Finasteride in Postmenopausal Women with Androgenetic Alopecia Journal of The American Academy of Dermatology · 2000

    Related research 3

    1. What Do We Know About 5-Alpha Reductase Inhibitors? Surgical and Cosmetic Dermatology · 2018
    2. Dutasteride in Androgenetic Alopecia: An Update Current Clinical Pharmacology · 2017
    3. The Preventive and Therapeutic Efficacy of Finasteride and Dutasteride in TRAMP Mice The FASEB Journal · 2013