The Impact of Monotherapies for Male Androgenetic Alopecia: A Network Meta-Analysis Study

    Aditya K. Gupta, Mary Bamimore, Tong Wang, Milton Talukder
    From the encyclopedia
    Dutasteride →

    Heavy duty finasteride that comes with higher risks

    Microneedling →

    technique to create small wounds in skin to activate collagen production and hair growth

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    Studysummary The study concluded that dutasteride 0.5 mg daily for 24 weeks was the most effective monotherapy for increasing hair density in men with androgenetic alopecia, compared to other interventions. Our plain-language summary of this paper — not a Tressless recommendation.
    This network meta-analysis of 41 studies evaluated the effectiveness of various monotherapies for male androgenetic alopecia (AGA) over 24 weeks. Dutasteride 0.5 mg once daily was found to be the most effective in increasing both total and terminal hair densities, outperforming finasteride 1 mg once daily and topical cetirizine 1% twice daily. While newer treatments like PRP, LLLT, microneedling, cetirizine, and Botox did not show significant differences compared to established treatments, the study highlights the potential dose-dependent impact of these therapies and the need for standardized protocols in future trials.
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