Safety of Antiandrogens for the Treatment of Female Androgenetic Alopecia with Respect to Gynecologic Malignancies

    May 2024 in “ Journal of clinical medicine
    S. Morteza Seyed Jafari, Kristine Heidemeyer, Robert E. Hunger, Pierre A. de Viragh
    TLDR Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.
    The review article evaluates the safety of antiandrogens for treating female androgenetic alopecia (FAGA) in patients with a history of gynecologic malignancies. Spironolactone is identified as a safe option, even for high-risk populations, with no significant association with breast or gynecologic cancers. However, the safety of other medications like 5-alpha-reductase inhibitors and androgen receptor blockers remains uncertain, necessitating further studies to confirm their long-term safety and efficacy. The review emphasizes the need for more research to develop optimal treatment protocols for FAGA patients with a history of gynecologic cancers.
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