Hormonal Therapy in Female Pattern Hair Loss

    Kevin R. Brough, Rochelle R. Torgerson
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    TLDR Hormonal therapies help treat female hair loss, but results are slow and vary.
    Female pattern hair loss (FPHL) is a common form of hair loss in women, characterized by hair thinning at the vertex of the scalp. Hormonal therapies, including 5-alpha-reductase inhibitors, androgen receptor blockers, estrogen, and oral contraceptive drugs, have been used to treat FPHL. The effectiveness of these therapies varies, and the only FDA-approved therapy is minoxidil. Patients should have reasonable expectations, as progress is slow and can take months or years to see significant improvement. Further research is needed to determine the optimal treatment approach.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 3 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Dec 2024 vs now (min + fin/dut)

      in Progress Pictures  23 upvotes 1 day ago
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      community For the ladies: Spironolactone for FPHL

      in Female  14 upvotes 8 years ago
      A 34 year old female with androgenic alopecia who has tried treatments such as Spironolactone, Desogen, Minoxidil and Finasteride in order to address her hair loss. It also details the experiences of other women taking Spironolactone for Female Pattern Hair Loss (FPHL).

      community One+ year 1mg Fin, Ketoconazole, and 3.75 Oral Min. I have DUPA. Switched from Topical to Oral Min.

      in Progress Pictures  142 upvotes 3 years ago
      A user's experience with hair loss treatments such as finasteride, ketoconazole, and oral minoxidil that have not yielded any results; other users suggest shaving the head or getting a wig, while others offer additional advice such as seeing a dermatologist, checking thyroid levels, switching to dutasteride and adding needling, and trying stemoxydine.

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