Hair Regrowth in a Male Patient with Extensive Androgenetic Alopecia on Estrogen Therapy

A male-to-female transsexual patient with extensive androgenetic alopecia (AGA) experienced full hair regrowth over completely alopecic scalp after being on estrogen therapy. The patient was also taking minoxidil, estrone, and Aldactone. The study suggests that adding estrogens to antiandrogen therapy may revitalize and maintain quiescent AGA hair follicles. The study also mentions that antimalarials are considered as systemic first-line treatment of cutaneous lupus erythematosus (CLE), while other medications, such as dapsone and retinoids, are among the second-line treatment options. One of the randomized controlled trials suggested that acitretin, an aromatic retinoid, may be as effective as hydroxychloroquine in the treatment of CLE.