Topical Estrogen Therapy for Androgenetic Alopecia in Menopausal Females

March 2004 in “ Dermatology ”

S. Georgala, Alexander C. Katoulis, C Georgala, Vassiliki Moussatou, E. Bozi, Nikolaos Stavrianeas

topical estrogens androgenetic alopecia estradiol valerate telogen rate anagen rate post-menopausal bleeding AGA hair loss estrogen therapy

TLDR Topical estrogen helps hair growth in menopausal women with no major side effects.

This study examined the efficacy and safety of topical estrogens as a treatment for androgenetic alopecia (AGA) in menopausal females. 75 postmenopausal women were randomized into three groups - one receiving treatment with an estradiol valerate lotion for 12 weeks, another group receiving treatment for 24 weeks, and a placebo group for 24 weeks. The results showed that there was a statistically significant difference between the treatment and placebo groups, with the treatment groups showing improvement in terms of decreased telogen rate and increased anagen rate. There were no significant side effects reported, although two patients did experience post-menopausal bleeding during the course of treatment.

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Research cited in this study

2 / 2 results

research Management of Androgenetic Alopecia

22 citations, May 2000 in “American Journal of Clinical Dermatology”

Treatments for common hair loss include minoxidil, finasteride, and hair transplantation.

research Treatment of Androgenetic Alopecia in Females in Reproductive Age with Topical Estradiolbenzoate, Prednisolone, and Salicylic Acid

1 citations, January 2000 in “PubMed”

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community Well… I Did It. Estrogen Saved My Hairline

in Transgender 717 upvotes 3 months ago

OP transitioned and used Spironolactone, Estradiol Valerate, Minoxidil, and dermarolling, resulting in significant hair regrowth. They advise this method may not be suitable for cis men.

community Found the solution tressbros - 1.5 years 2.5mg oral minox, 5mg finasteride, 8mg estradiol valerate (weekly)

in Transgender 591 upvotes 10 months ago

The conversation discusses a transgender individual's successful hair loss treatment over 1.5 years using 2.5mg oral minoxidil, 5mg finasteride, and 8mg weekly injectable estradiol valerate. Some users debate the appropriateness of this approach within the group's goals, while others support the individualized treatment and its additional benefits for transgender individuals.

community DHT/Testosterone levels in scalp Fin VS Dut.

in Finasteride/Dutasteride 60 upvotes 5 months ago

Dutasteride raises scalp testosterone by 99%, which may not be ideal for those sensitive to all androgens. Some argue finasteride's balancing act might be better, while others believe dutasteride is superior for hair regrowth.

community Is it possible to create an estrogen mesotherapy/topical that doesn't go systemic?

in Research/Science 6 upvotes 1 month ago

The conversation discusses the potential of using topical estrogen treatments for hair loss without systemic absorption, highlighting challenges and possible solutions like using estriol. It also mentions other treatments like topical finasteride, microneedling, and scalp massage, while noting the limitations and side effects of current options.

community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

in Treatment 47 upvotes 7 months ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

in Progress Pictures 83 upvotes 2 years ago

Treating Seborrheic Dermatitis, a fungal scalp condition which can cause hair loss. Treatments discussed include antifungal shampoos, cold showers, exfoliating the scalp, taking Vitamin D, and stimulating the prostate through the anus.

Related Research

1 / 1 results

research Topical Estrogen Therapy for Androgenetic Alopecia in Menopausal Females

22 citations, March 2004 in “Dermatology”

Topical estrogen helps hair growth in menopausal women with no major side effects.