Comparative Analysis of Low-Dose Oral Minoxidil with Spironolactone Versus Finasteride or Dutasteride in Female Androgenetic Alopecia Management

    September 2024 in “ Archives of Dermatological Research
    Deesha Desai, Ambika Nohria, Michelle Sikora, Nnaemeka Anyanwu, Jerry Shapiro, Kristen I. Lo Sicco
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    TLDR Both treatment combinations improved hair growth similarly and were safe.
    This study compared the efficacy and safety of low-dose oral minoxidil (LDOM) combined with either spironolactone or finasteride/dutasteride in treating female androgenetic alopecia (AGA). Both combination therapies showed similar improvements in hair growth and had comparable safety profiles. Although the group using LDOM with finasteride/dutasteride experienced a greater average increase in hair width and density, these differences were not statistically significant. The findings support the use of LDOM with either spironolactone or finasteride/dutasteride for female AGA and highlight the need for further research to confirm these results and evaluate long-term outcomes.
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