Insulin-Like Growth Factor 1 (IGF-1) in Hair Regeneration: Mechanistic Pathways and Therapeutic Potential

September 2025 in “ Current Issues in Molecular Biology ”

Wen‐Ping Hsieh, Wuqi Qiu, Ivona Percec, Tsong‐Min Chang

Insulin-like Growth Factor 1 IGF-1 androgenetic alopecia AGA dermal papilla cells hair follicle proliferation vascularization PI3K/Akt pathway MAPK/ERK pathway apoptosis VEGF expression topical IGF-1 treatments follicular degeneration growth factors combination therapies

Studysummary This study highlights IGF-1's role in promoting hair follicle proliferation, vascularization, and growth, suggesting its potential as a treatment target for hair loss disorders like androgenetic alopecia, though more research on delivery methods and long-term effects is needed.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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