Hair Growth Promotion Effect of Nelumbinis Semen Extract with High Antioxidant Activity

March 2021 in “ Evidence-based Complementary and Alternative Medicine ”

Hyeon Ju Park, Guang-Ri Jin, Jae Hyun Jung, Su Bin Hwang, Sang Ho Lee, Bog‐Hieu Lee

Nelumbinis Semen extract antioxidant activity hair follicle dermal papilla cells Vascular Endothelial Growth Factor Insulin-like Growth Factor 1 Transforming Growth Factor Beta 1 NS extract VEGF IGF-1 TGF-β1

TLDR Nelumbinis Semen extract helps hair grow and could prevent hair loss.

The 2021 study "Hair Growth Promotion Effect of Nelumbinis Semen Extract with High Antioxidant Activity" found that Nelumbinis Semen (NS) extract significantly promotes hair growth. The extract, which has high antioxidant activity, was tested in vitro on human hair follicle dermal papilla cells and in vivo on mice. The results showed increased cell proliferation and hair follicle count, as well as longer hair shafts in mice. The NS extract also increased the mRNA expression levels of Vascular Endothelial Growth Factor (VEGF) and Insulin-like Growth Factor 1 (IGF-1), which enhance hair growth, and decreased the expression level of Transforming Growth Factor Beta 1 (TGF-β1), which suppresses hair follicle proliferation. The study concluded that NS extract could potentially be used as a natural remedy for promoting hair growth and preventing hair loss.

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