The Preclinical and Clinical Effects of Herbal Product Containing Rosa Multiflora Roots Extracts on Hair Growth Promotion

April 2012 in “ Korean journal of medicinal crop science/Han-gug yagyong jagmul hag-hoeji ”

Joong Hark Kim, Sung Kyu Hong, Sung Jue Hwang, Sang Wook Son, Yong Choi

Rosa multiflora roots extracts RMHP hair growth promotion hair density hair thickness C57BL/6 mice clinical trial preclinical trial Rosa multiflora herbal product hair growth hair loss prevention

Studysummary This study found that the herbal product containing Rosa multiflora roots extract improved hair density and thickness and significantly promoted hair growth in both mice and human patients after 16 weeks of treatment.

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The study evaluated the hair growth promotion effects of a herbal product containing Rosa multiflora roots extracts (RMHP) through preclinical and clinical trials. In animal experiments with 4-week-old male C57BL/6 mice, RMHP significantly stimulated hair growth compared to the negative control. In a clinical trial involving 37 patients over 16 weeks, RMHP significantly increased hair density from 104.3 ± 4.7 FU/㎠ to 125.0 ± 4.9 FU/㎠ and hair thickness from 0.055 ± 0.002 ㎜ to 0.066 ± 0.003 ㎜. Clinical photo-interpretation showed significant improvement in hair growth, indicating RMHP's effectiveness in preventing hair loss and promoting hair growth.

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