Collagen Hydrolysate from Mozambique Tilapia Scales Improves Hair and Skin Health

August 2023 in “ Marine drugs ”

Su Bin Hwang, Hyeon Ju Park, Bog‐Hieu Lee

Studysummary In this study, fish-derived collagen hydrolysate from tilapia scales improved hair growth and skin health in both cellular and mouse models, reducing oxidative stress and inflammation while enhancing hair quality and promoting beneficial gene expression. Our plain-language summary of this paper — not a Tressless recommendation.

The study investigated the effects of collagen hydrolysate (CH) derived from Mozambique tilapia scales on hair and skin health in human dermal papilla cells and C57BL/6 mice. CH was found to increase catalase activity, IGF-1 and VEGF levels, and decrease TGF-β1, TNF-α, and IL-1β expression. In mice, CH improved hair growth index, length, diameter, weight, and density, and reduced hair damage. It also up-regulated IGF-1, VEGF, Elastin, and HAS2 mRNA expression while down-regulating TNF-α and IL-1β. The study concluded that CH has potential in alleviating oxidative stress, promoting hair growth, and enhancing skin health.

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