VEGFR-2 Is in a State of Activation in Hair Follicles, Sebaceous Glands, Eccrine Sweat Glands, and Epidermis from Human Scalp: An In Situ Immunohistochemistry Study of Phosphorylated VEGFR-2
TLDR VEGFR-2 is active in hair follicles, sebaceous glands, sweat glands, and skin on the human scalp.
The study found that VEGFR-2 was activated in hair follicles, sebaceous glands, eccrine sweat glands, and the epidermis of the human scalp, as shown by in situ immunohistochemistry detecting phosphorylated VEGFR-2. This activation suggested a role for VEGFR-2 in the physiological processes of these structures, potentially influencing hair growth and scalp health. The study included scalp specimens from 11 donors aged 20-35 years, indicating that VEGFR-2 signaling might be crucial for the routine functions of the epidermis and its appendages, though further research was needed to understand the specific regulatory mechanisms.
