Hair Growth Effect and the Mechanisms of Rosa Rugosa Extract in DHT-Induced Alopecia Mice Model
October 2024
in “
International Journal of Molecular Sciences
”
Rosa rugosa extract DHT alopecia VEGF EGF IGF-1 DKK1 IL-6 ERK AKT Wnt/β-catenin anagen phase RWE dihydrotestosterone vascular endothelial growth factor epidermal growth factor insulin-like growth factor 1 dickkopf-related protein 1 interleukin 6 extracellular signal-regulated kinase protein kinase B Wnt signaling pathway
Studysummary In this study, Rosa rugosa water extract improved hair length and thickness in a mouse model of DHT-induced alopecia by enhancing the expression of hair growth-promoting factors while inhibiting growth-suppressive proteins, suggesting its potential as a natural therapy for hair loss prevention.
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