Studysummary This review discusses the roles of androgens and androgen receptors in skin-related disorders and suggests that targeting androgen receptors may be a more effective treatment strategy.
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Research cited in this study 45
- Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia Science Translational Medicine · 2012
- Topical Eflornithine Hydrochloride Improves the Effectiveness of Standard Laser Hair Removal for Treating Pseudofolliculitis Barbae: A Randomized, Double-Blinded, Placebo-Controlled Trial Journal of the American Academy of Dermatology · 2012
- Androgen Receptor Gene Polymorphisms and Risk for Androgenetic Alopecia: A Meta-Analysis Clinical and Experimental Dermatology · 2011
- Ethinylestradiol/Chlormadinone Acetate for Use in Dermatological Disorders American Journal of Clinical Dermatology · 2011
- Acne-Associated Syndromes: Models for Better Understanding of Acne Pathogenesis Journal of The European Academy of Dermatology and Venereology · 2010
- Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla Journal of Dermatological Science · 2010
- Nutrition and Acne: The Role of Diet in Acne Development Clinics in dermatology · 2010
- SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder Cell · 2010
- Selective Induction of Apoptosis in the Hamster Flank Sebaceous Gland Organ by a Topical Liposome 5-Alpha-Reductase Inhibitor: A Treatment Strategy for Acne Journal of Dermatology · 2010
- Biosynthesis of Dihydrotestosterone by a Pathway That Does Not Require Testosterone as an Intermediate in the SZ95 Sebaceous Gland Cell Line Journal of Investigative Dermatology · 2009
- Role of Insulin, Insulin-Like Growth Factor-1, Hyperglycemic Food, and Milk Consumption in the Pathogenesis of Acne Vulgaris Experimental dermatology · 2009
- Role of FGFR2-Signaling in the Pathogenesis of Acne Dermato-endocrinology · 2009
- Keratinocyte Growth Inhibition Through the Modification of Wnt Signaling by Androgen in Balding Dermal Papilla Cells The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 2009
- A Comparison Between Finasteride, Flutamide, and Finasteride Plus Flutamide Combination in the Treatment of Hirsutism Journal of Endocrinological Investigation · 2009
- Male-Pattern Baldness Susceptibility Locus at 20p11 Nature Genetics · 2008
- Hormonal Therapy for Acne Seminars in Cutaneous Medicine and Surgery · 2008
- Genome-Wide Scan and Fine-Mapping Linkage Study of Androgenetic Alopecia Reveals a Locus on Chromosome 3q26 American Journal of Human Genetics · 2008
- Men With Kennedy Disease Have a Reduced Risk of Androgenetic Alopecia British Journal of Dermatology · 2007
- Androgenetic Alopecia: Clinical Features, Classification, and Treatments Endocrinology and Metabolism Clinics of North America · 2007
- A Randomized Bilateral Vehicle-Controlled Study of Eflornithine Cream Combined with Laser Treatment Versus Laser Treatment Alone for Facial Hirsutism in Women Journal of the American Academy of Dermatology · 2007
- Inhibition of 5α-Reductase Activity in SZ95 Sebocytes and HaCaT Keratinocytes In Vitro Hormone and metabolic research · 2007
- Sexual Hormones in Human Skin Hormone and metabolic research · 2007
- The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride Journal of The American Academy of Dermatology · 2006
- Treatment of Hirsutism and Acne in Hyperandrogenism Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism · 2006
- Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia American Journal of Human Genetics · 2005
- Androgen Action on Human Skin – From Basic Research to Clinical Significance Experimental dermatology · 2004
- Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
- Cutaneous Androgen Metabolism: Basic Research And Clinical Perspectives The journal of investigative dermatology/Journal of investigative dermatology · 2002
- Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing The Journal of clinical investigation/The journal of clinical investigation · 2002
- Sebocytes Are the Key Regulators of Androgen Homeostasis in Human Skin The journal of investigative dermatology/Journal of investigative dermatology · 2001
- Polymorphism of the Androgen Receptor Gene Is Associated with Male Pattern Baldness Journal of Investigative Dermatology · 2001
- Comparison of Spironolactone, Flutamide, and Finasteride Efficacy in the Treatment of Hirsutism: A Randomized, Double-Blind, Placebo-Controlled Trial The Journal of Clinical Endocrinology and Metabolism · 2000
- Current Aspects of Antiandrogen Therapy in Women Current Pharmaceutical Design · 1999
- Androgen Receptor Polymorphisms (CAG Repeat Lengths) in Androgenetic Alopecia, Hirsutism, and Acne Journal of Cutaneous Medicine and Surgery · 1998
- Evidence of Heterogeneity and Quantitative Differences of the Type 1 5α-Reductase Expression in Cultured Human Skin Cells: Evidence of Its Presence in Melanocytes Journal of Investigative Dermatology · 1998
- Incidence of Increased Androgen Levels in Patients Suffering from Acne Dermatology · 1998
- Other Antiandrogens: Alternative Treatments for Acne and Hirsutism Dermatology · 1998
- Balding Hair Follicle Dermal Papilla Cells Contain Higher Levels of Androgen Receptors Than Those From Non-Balding Scalp Journal of Endocrinology · 1998
- Antiandrogen Therapy in Dermatology International Journal of Dermatology · 1996
- The 5 Alpha-Reductase System and Its Inhibitors Dermatology · 1996
- Cultured Dermal Papilla Cells From Androgen-Dependent Human Hair Follicles Contain More Androgen Receptors Than Those From Non-Balding Areas Of Scalp Journal of Endocrinology/Journal of endocrinology · 1992
- Selective Inhibition by Minoxidil of Prostacyclin Production by Cells in Culture Biochemical Pharmacology · 1988
- Spironolactone in the Treatment of Hirsutism Acta obstetricia et gynecologica Scandinavica · 1986
- The Effects of Two Doses of Spironolactone on Serum Androgens and Anagen Hair in Hirsute Women Fertility and sterility · 1985
- The Inheritance Of Common Baldness: To Be Or Not To Be? Journal of the American Academy of Dermatology · 1984