A Comparison Between Finasteride, Flutamide, and Finasteride Plus Flutamide Combination in the Treatment of Hirsutism

January 2009 in “ Journal of Endocrinological Investigation ”

Kursad Unluhizarci, Deniz Ozel, Fatih Tanriverdi, Zuleyha Karaca, Fahrettin Kelestimur

finasteride flutamide androgenic activity hirsutism Propecia

TLDR Flutamide works better than finasteride for hirsutism, and combining both is slightly better but not much.

This study compared the effectiveness of finasteride, flutamide, and a combination of both drugs in treating hirsutism in women. The study found that flutamide was more effective than finasteride, and the combination of both drugs was not significantly better than flutamide alone but better than finasteride alone. The study suggests that the combination of finasteride and flutamide may be complementary in reducing androgenic activity in patients with hirsutism.

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Research cited in this study

11 / 11 results

research Finasteride Treatment for One Year in 35 Hirsute Patients

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Low-dose finasteride effectively reduces hirsutism without serious side-effects.

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Diane 35 plus finasteride is more effective for treating hirsutism.

research Screening for 21-Hydroxylase-Deficient Nonclassic Adrenal Hyperplasia Among Hyperandrogenic Women: A Prospective Study

216 citations , November 1999 in “Fertility and Sterility”

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

research Comparison of Finasteride Versus Flutamide in the Treatment of Hirsutism

75 citations , October 1999 in “European journal of endocrinology”

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

research Treatment of Hirsutism: Comparisons Between Different Antiandrogens with Central and Peripheral Effects

75 citations , March 1999 in “Fertility and sterility”

Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.

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