Spironolactone in the Treatment of Hirsutism

    Michael Chapman, Maurice Katz, Mitchell Dowsett, William M. Hague, S. L. Jeffcoate, C. J. Dewhurst
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    Spironolactone →

    powerful topical and oral anti-androgen used mostly by women

    Cyproterone →

    a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

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    Studysummary In this study, spironolactone treatment reduced hair growth in 17 out of 30 patients with hirsutism, but was less effective compared to cyproterone acetate–estrogen therapy.
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