Current Aspects of Antiandrogen Therapy in Women
January 1999
in “
Current Pharmaceutical Design
”
TLDR Antiandrogen therapy is effective and well tolerated for treating women's androgenic disorders like hirsutism, acne, and hair loss.
In 1998, antiandrogen therapy was identified as a promising treatment for androgenic disorders in women, which can cause social and psychological distress, as well as serious skin, reproductive, and metabolic abnormalities. Clinical studies demonstrated the effectiveness of various agents, including spironolactone, cyproterone acetate, flutamide, and finasteride, in treating hirsutism, acne, androgenic alopecia, and ovulatory dysfunction in hyperandrogenic women. Comparative clinical studies suggested that these agents, especially in low-dose regimens, were well tolerated and had potential for broader clinical use.