TLDR Antiandrogen therapy is effective and well tolerated for treating women's androgenic disorders like hirsutism, acne, and hair loss.
In 1998, antiandrogen therapy was identified as a promising treatment for androgenic disorders in women, which can cause social and psychological distress, as well as serious skin, reproductive, and metabolic abnormalities. Clinical studies demonstrated the effectiveness of various agents, including spironolactone, cyproterone acetate, flutamide, and finasteride, in treating hirsutism, acne, androgenic alopecia, and ovulatory dysfunction in hyperandrogenic women. Comparative clinical studies suggested that these agents, especially in low-dose regimens, were well tolerated and had potential for broader clinical use.
31 citations
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June 2015 in “British Journal of Dermatology” Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.
14 citations
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January 2008 in “Dermatology Online Journal” Hormonal therapies like cyproterone acetate and spironolactone may help some women with hair loss, but finasteride 1mg is not useful, and the effectiveness of other treatments is still unclear.
24 citations
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March 2002 in “Expert opinion on investigational drugs” Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.
20 citations
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January 1999 in “Current Pharmaceutical Design” Antiandrogen therapy is effective and well tolerated for treating women's androgenic disorders like hirsutism, acne, and hair loss.
11 citations
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January 1998 in “Dermatology” Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.
