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Glossary Androgenic Disorders

refer to conditions caused by abnormal male hormone activity

Androgenic disorders refer to medical conditions caused by the abnormal production or action of androgens, which are male sex hormones like testosterone. These disorders can lead to various symptoms, including excessive hair growth (hirsutism) in women, hair loss (androgenic alopecia) in both men and women, and other hormonal imbalances that can affect reproductive and overall health.

Related Terms

Research

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Treatment of Androgenic Disorders with Dexamethasone: Dose-Response Relationship for Suppression of Dehydroepiandrosterone Sulfate

research Treatment of androgenic disorders with dexamethasone: Dose-response relationship for suppression of dehydroepiandrosterone sulfate

18 citations , January 1990 in “Journal of The American Academy of Dermatology”

This study found that dexamethasone effectively suppressed DHEAS levels in women with elevated levels using much lower doses than previously thought, without significant adverse effects.

research Androgenic disorders of women: Diagnostic and therapeutic decision making

17 citations , January 1995 in “The American Journal of Medicine”

This review discusses the management of androgenic disorders in women, highlighting that treatment is generally more effective than recognized, though improvement may take weeks or months to appear.

research A study of androgenic signs and disorders in Greek female patients with acne

2 citations , January 2018 in “Journal of The European Academy of Dermatology and Venereology”

This letter discusses androgenic signs and disorders in Greek female patients with acne and reports no new clinical findings.

Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders

research Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders

November 2023 in “ACS Omega”

This study reported that a novel cationic liposome formulation for delivering encapsulated Cas9 protein and sgRNA successfully decreased SRD5α2 mRNA expression by 29.7% in vitro, suggesting a potential alternative treatment option for conditions like prostate cancer and benign prostatic hyperplasia without current drug side effects.

Androgenic Disorders: Comprehensive Coverage of Syndromes in Women

research Androgenic disorders

July 1996 in “Trends in Endocrinology and Metabolism”

The book is a valuable reference on androgenic disorders for professionals but not suitable for laypeople or medical students.

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Community Join

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community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Arthritis drug restores 100% hair on 1 in 5 alopecia patients in global trial

150 upvotes 2 weeks ago

An arthritis drug, Rinvoq, restores hair in some alopecia areata patients but is not effective for androgenetic alopecia. It is used for autoimmune-related skin disorders, but its high cost and lack of insurance coverage are issues.

community I Get Side-Effects from Anti-Androgens

8 upvotes 6 years ago

Someone looking for solutions to their hair loss, who has tried and failed to tolerate anti-androgen treatments such as finasteride, CB-03-01, RU58841, and Eucapil. The user is seeking advice and understanding of their extreme sensitivity to these treatments.

community My Theory Of Androgenic Alopecia

16 upvotes 9 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community Sexual Dysfunction in Those with Androgenetic Alopecia on Dutasteride Versus Finasteride

in Finasteride/Dutasteride 113 upvotes 1 year ago

Dutasteride and finasteride have similar risks of sexual dysfunction for treating androgenetic alopecia. Users experience varying side effects, indicating individual differences in drug reactions.

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Learn

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learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

learn Overview

learn Metformin

diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

Does metformin help control DHT levels that trigger androgenic alopecia? Metformin has been shown to lower circulating androgens in women with PCOS, but no published study has measured scalp DHT, 5-alpha reductase activity in the follicle, or hair density in anyone taking it — so its effect on pattern hair loss is untested, and it is not a DHT blocker.

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Vitamin D

vitamin you should probably be taking for general health might also help your hair a little

learn Finasteride

Does hair strand thickness decrease in men with androgenic alopecia? Can finasteride help restore it? Androgenic alopecia thins hair strands by miniaturizing follicles. The pivotal finasteride trials (1,553 men, 1 mg/day, two years) report increased hair counts and improved assessed appearance, but they measured density, not the diameter of individual strands, so the effect on thickness itself is not established.

learn Spironolactone

Who can safely use spironolactone for hair thinning and androgen-related hair loss? Women with androgen-related hair loss can safely use spironolactone under medical supervision.

learn Argan oil

Argan oil: Is it useful for androgenic alopecia, or just for making hair look nice? Argan oil primarily improves hair appearance but lacks proven effectiveness for androgenic alopecia.

learn Microneedling

Does microneedling help with all types of alopecia, or only androgenic alopecia? Microneedling is most effective for androgenic alopecia, with limited evidence for other types.

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Clinics

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Trichology
The Pharmacy for Hair Loss & Scalp Disorders, PLLC.Brentwood, TN · US

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