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Glossary Hyperandrogenism

elevated androgen levels causing symptoms like excessive hair growth

Hyperandrogenism, also known as Androgen Excess, refers to a condition characterized by elevated levels of androgens (male hormones such as testosterone) in the body. This hormonal imbalance can lead to symptoms such as excessive hair growth (hirsutism), acne, and scalp hair thinning in women. It is often associated with conditions like polycystic ovary syndrome (PCOS) and can have significant implications for reproductive and metabolic health.

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Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline

research Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline

1744 citations , August 2006 in “The Journal of Clinical Endocrinology and Metabolism”

This review discusses definitions of polycystic ovary syndrome and reports no new clinical results; the authors support using modified 1990 NIH criteria and acknowledge ongoing evolution as research advances.

research Relative Prevalence of Different Androgen Excess Disorders in 950 Women Referred because of Clinical Hyperandrogenism

352 citations , January 2006 in “The Journal of Clinical Endocrinology and Metabolism”

This study reported that classic anovulatory PCOS was the most common androgen excess disorder, followed by mild ovulatory PCOS and idiopathic hyperandrogenism, among patients evaluated for clinical hyperandrogenism.

research Screening for 21-hydroxylase–deficient nonclassic adrenal hyperplasia among hyperandrogenic women: a prospective study

216 citations , November 1999 in “Fertility and Sterility”

This study found that a basal 17-hydroxyprogesterone level is effective for screening nonclassic adrenal hyperplasia in women, with a 4 ng/mL cutoff providing high specificity and positive predictive value.

research Polycystic ovarian syndrome: Correlation between hyperandrogenism, insulin resistance and obesity

195 citations , November 2019 in “Clinica Chimica Acta”

This review discusses the interplay of hyperandrogenism, insulin resistance, obesity, and their role in polycystic ovary syndrome, but presents no new clinical results.

Prevalence of Hyperandrogenemia in Polycystic Ovary Syndrome Diagnosed by the National Institutes of Health 1990 Criteria

research Prevalence of hyperandrogenemia in the polycystic ovary syndrome diagnosed by the National Institutes of Health 1990 criteria

118 citations , February 2009 in “Fertility and Sterility”

This study found that approximately 75% of women with PCOS exhibited hyperandrogenemia, with free testosterone being the most frequently elevated marker.

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community Possible explaination for Finasteride Reflex Hyperandrogenicity

6 upvotes 4 years ago

The user has been using finasteride and minoxidil for hair loss but experienced worsening temple recession. They suspect they might be more sensitive to testosterone and are considering trying RU58841 or CB 03 01 as additional treatments.

community Dutasteride is amazing even for women with FAGA!

in Female 151 upvotes 1 year ago

Dutasteride significantly improved hair health and reduced shedding for a woman with PCOS and hyperandrogenism, without causing depression or anxiety, unlike finasteride. Dutasteride also helped with PMDD symptoms and had no side effects, though it changed hair texture.

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learn RU58841

a potent but unapproved and potentially problematic topical anti-androgen

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

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