Search

for
Search:

Did you mean Hyperandrogenism?

Glossary Hyperandrogenism

elevated androgen levels causing symptoms like excessive hair growth

Hyperandrogenism, also known as Androgen Excess, refers to a condition characterized by elevated levels of androgens (male hormones such as testosterone) in the body. This hormonal imbalance can lead to symptoms such as excessive hair growth (hirsutism), acne, and scalp hair thinning in women. It is often associated with conditions like polycystic ovary syndrome (PCOS) and can have significant implications for reproductive and metabolic health.

Related Terms

Sort by

Research

30 / 1000+ results

Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline

research Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline

1744 citations , August 2006 in “The Journal of Clinical Endocrinology and Metabolism”

This review discusses definitions of polycystic ovary syndrome and reports no new clinical results; the authors support using modified 1990 NIH criteria and acknowledge ongoing evolution as research advances.

research Relative Prevalence of Different Androgen Excess Disorders in 950 Women Referred because of Clinical Hyperandrogenism

352 citations , January 2006 in “The Journal of Clinical Endocrinology and Metabolism”

This study reported that classic anovulatory PCOS was the most common androgen excess disorder, followed by mild ovulatory PCOS and idiopathic hyperandrogenism, among patients evaluated for clinical hyperandrogenism.

research Screening for 21-hydroxylase–deficient nonclassic adrenal hyperplasia among hyperandrogenic women: a prospective study

216 citations , November 1999 in “Fertility and Sterility”

This study found that a basal 17-hydroxyprogesterone level is effective for screening nonclassic adrenal hyperplasia in women, with a 4 ng/mL cutoff providing high specificity and positive predictive value.

research Polycystic ovarian syndrome: Correlation between hyperandrogenism, insulin resistance and obesity

195 citations , November 2019 in “Clinica Chimica Acta”

This review discusses the interplay of hyperandrogenism, insulin resistance, obesity, and their role in polycystic ovary syndrome, but presents no new clinical results.

Prevalence of Hyperandrogenemia in Polycystic Ovary Syndrome Diagnosed by the National Institutes of Health 1990 Criteria

research Prevalence of hyperandrogenemia in the polycystic ovary syndrome diagnosed by the National Institutes of Health 1990 criteria

118 citations , February 2009 in “Fertility and Sterility”

This study found that approximately 75% of women with PCOS exhibited hyperandrogenemia, with free testosterone being the most frequently elevated marker.

research Treatment of hyperandrogenic alopecia in women

108 citations , January 2003 in “Fertility and Sterility”

This study found that flutamide at 250 mg daily modestly improved hair thinning in premenopausal women with hyperandrogenic alopecia over one year, while cyproterone acetate and finasteride were not effective.

research Hyperandrogenism and insulin resistance modulate gravid uterine and placental ferroptosis in PCOS-like rats

104 citations , June 2020 in “Journal of Endocrinology”

This study suggests that in rats, maternal hyperandrogenism and insulin resistance lead to activation of ferroptosis in the gravid uterus and placenta, mediated by different molecular and cellular mechanisms.

research Hyperandrogenism and Polycystic Ovary Syndrome in Women with Type 1 Diabetes Mellitus

96 citations , February 2007 in “The Journal of Clinical Endocrinology & Metabolism”

This review discusses the high prevalence of androgen excess and PCOS in women with type 1 diabetes but reports no new clinical findings; the authors highlight the underdiagnosis of hyperandrogenism in these patients.

research American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the Diagnosis and Treatment of Hyperandrogenic Disorders

89 citations , March 2001 in “Endocrine practice”

This article provides diagnosis and treatment guidelines for hyperandrogenic disorders in women but reports no new clinical results; it offers a summary of accepted scientific information and suggestions for clinical practice.

research Diagnosis of hyperandrogenism: clinical criteria

85 citations , June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism”

This review outlines the challenges in diagnosing hyperandrogenism in women, focusing on its manifestations like hirsutism, acne, and virilization, but provides no new results.

research Diagnosis of hyperandrogenism: Biochemical criteria

77 citations , June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism”

This review discusses the importance of androgen production and metabolism in hyperandrogenism, the use of specific serum markers for diagnosis, and the need for improved assays for clinical testing, but reports no new results.

research A comparison of the relative efficacy of antiandrogens for the treatment of acne in hyperandrogenic women

74 citations , August 2002 in “Clinical Endocrinology”

In this study, low doses of cyproterone acetate with ethinylestradiol were as effective as low-dose flutamide in reducing acne severity in hyperandrogenic women, while finasteride was less effective.

research The Role of Oral Contraceptives in the Treatment of Hyperandrogenic Disorders

57 citations , January 1995 in “The American journal of medicine”

This study discusses the use of oral contraceptives as a treatment for hyperandrogenism, showing improvement in hirsutism and acne for many women and possibly providing metabolic benefits with certain formulations.

research Treatment of hirsutism and acne in hyperandrogenism

54 citations , June 2006 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism”

This review discusses the management of hirsutism and acne in women with polycystic ovary syndrome, highlighting the partial effectiveness of current treatments and suggesting a combined approach of medication and hair removal.

research Association of biochemical hyperandrogenism with type 2 diabetes and obesity in Chinese women with polycystic ovary syndrome

52 citations , November 2009 in “International journal of gynaecology and obstetrics”

This study found that hyperandrogenemia in Chinese women with PCOS is associated with higher risks of type 2 diabetes and obesity, suggesting it should be prioritized in managing PCOS-related infertility.

research Hyperandrogenism in polycystic ovarian syndrome and role of CYP gene variants: a review

49 citations , November 2019 in “Egyptian Journal of Medical Human Genetics”

This review discusses the role of CYP gene polymorphisms in exacerbating hyperandrogenism in women with PCOS and reports no clinical results; further validation of this hypothesis is needed.

research Role of androgens in female-pattern androgenetic alopecia, either alone or associated with other symptoms of hyperandrogenism

47 citations , December 2000 in “Archives of Dermatological Research”

This study found that women with androgenetic alopecia showed higher levels of certain hormones and lower levels of sex hormone-binding globulin than healthy controls, potentially linking these factors to alopecia severity.

17-Hydroxyprogesterone Responses to Gonadotropin-Releasing Hormone Reveal Distinct Phenotypes of Functional Ovarian Hyperandrogenism and Polycystic Ovary Syndrome

research 17-Hydroxyprogesterone Responses to Gonadotropin-Releasing Hormone Disclose Distinct Phenotypes of Functional Ovarian Hyperandrogenism and Polycystic Ovary Syndrome

42 citations , September 2007 in “The Journal of Clinical Endocrinology and Metabolism”

This study found that women with PCOS who have an exaggerated 17-hydroxyprogesterone response to buserelin exhibit more severe hyperandrogenemia, increased insulin secretion, and reduced insulin sensitivity.

research A Detailed Investigation of Hirsutism in a Turkish Population: Idiopathic Hyperandrogenemia as a Perplexing Issue

42 citations , October 2004 in “Experimental and Clinical Endocrinology & Diabetes”

In this study, PCOS was the most common cause of hirsutism among Turkish women, but about 17% had idiopathic hyperandrogenemia with no clear cause identified.

research Shorter CAG repeats in the androgen receptor gene may enhance hyperandrogenicity in polycystic ovary syndrome

37 citations , January 2008 in “Gynecological Endocrinology”

This study found that in women with polycystic ovary syndrome, shorter CAG repeat lengths in the androgen receptor gene were associated with lower dihydrotestosterone and androstenedione levels, but a higher prevalence of acne and hirsutism.

research Differential Diagnosis of Hyperandrogenism in Women with Polycystic Ovary Syndrome

35 citations , March 2012 in “Experimental and Clinical Endocrinology & Diabetes”

This article discusses various causes of hyperandrogenism in women and highlights diagnostic considerations for conditions such as PCOS, NCCAH, Cushing's disease, and androgen-secreting tumors, without reporting new clinical results.

research Prevalence of Hyperandrogenic States in Late Adolescent and Young Women: Epidemiological Survey on Italian High-School Students

34 citations , February 2013 in “The Journal of Clinical Endocrinology and Metabolism”

This study estimates the prevalence of hyperandrogenic states in late adolescent and young females, revealing that these disorders often begin at a young age.

The Frequency of Metabolic Syndrome Is Higher Among Brazilian Women With PCOS, Menstrual Irregularity, and Hyperandrogenism

research The Frequency of Metabolic Syndrome is Higher Among PCOS Brazilian Women With Menstrual Irregularity Plus Hyperandrogenism

32 citations , November 2011 in “Reproductive Sciences”

The study found that among young Brazilian women, the likelihood of metabolic syndrome in those with PCOS is strongly associated with BMI and the phenotype involving menstrual irregularity and hyperandrogenism.

research Effects of two estroprogestins containing ethynilestradiol 30mug and drospirenone 3 mg and ethynilestradiol 30mug and chlormadinone 2 mg on skin and hormonal hyperandrogenic manifestations

31 citations , January 2008 in “Gynecological endocrinology”

In this study, two different estroprogestin treatments significantly improved skin conditions and decreased androgen levels in hyperandrogenic women, with EE/DRSP showing more pronounced hormonal changes and skin improvements compared to EE/CMA.