June 2024 in “Journal of psychiatric research” Short-term finasteride use in male rats caused anxiety, depression, and memory problems.
May 2024 in “Journal of clinical medicine” Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.
Stopping finasteride and closing PFO can help prevent strokes in young adults.
May 2024 in “European urology focus” Drugs for prostate enlargement and hair loss were not linked to increased risk of depression or suicide.
March 2024 in “Journal of Endocrinological Investigation” Finasteride treatment in rats changed the expression of genes related to psychiatric and neurological functions, and these changes persisted after stopping the drug.
March 2024 in “Healthcare” Stem cell treatment improved life quality and sexual function in women with hair loss.
Early-onset baldness is linked to genetics, lifestyle, and can indicate higher risk for heart and metabolic diseases, and affects mental health.
March 2024 in “Facial plastic surgery clinics of North America” Finasteride and minoxidil are approved treatments for hair loss, and hair transplants can be effective but require careful patient selection.
March 2024 in “Journal of the American Academy of Dermatology” Taking medication for hair loss might cause sexual problems.
December 2023 in “JAAD International” Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.
November 2023 in “Clinical, Cosmetic and Investigational Dermatology” A man's rash caused by Finasteride improved after stopping the drug and starting new treatments.
November 2023 in “Frontiers in Neuroendocrinology” Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.
3 citations,
September 2023 in “International journal of impotence research” Post-finasteride syndrome causes lasting sexual, mental, and physical issues, needing more research for solutions.
August 2023 in “Psychology, Health & Medicine” Hair loss (androgenetic alopecia) mildly to moderately affects men's quality of life but not significantly their mental health.
August 2023 in “International journal of impotence research” Many dermatologists believe finasteride can cause sexual side effects and counsel patients about them.
April 2023 in “Nigerian Journal of Clinical Practice” Hair loss in adults is linked to heart disease risk factors like unhealthy blood fats, lack of exercise, and alcohol use. It's also slightly more common in people with metabolic syndrome. As people age, hair loss gets worse. In men, severe hair loss is tied to high blood pressure and a larger waist. In women, it's tied to higher body weight. People with hair loss should be checked for unhealthy blood fats and advised to avoid alcohol and inactivity.
1 citations,
March 2023 in “Scientific Reports” Finasteride may increase the risk of suicide or severe self-harm in men with mood disorders but not in the general population.
December 2022 in “PubMed” December 2022 in “JAMA network open” November 2022 in “Frontiers in Medicine” 2 citations,
May 2022 in “International Journal of Impotence Research” 1 citations,
March 2022 in “Dermatology Research and Practice” 
February 2022 in “International Journal of Andrology” Finasteride, a hair loss drug, has unaddressed sexual side effects due to the manufacturer's inadequate safety measures and lack of additional studies.
January 2022 in “Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria” Androgenetic Alopecia (AGA) greatly lowers quality of life, causing stress and low self-esteem, with those seeking treatment experiencing more impairment.
1 citations,
January 2022 in “Clinical and Experimental Dermatology” Finasteride helps reduce hidradenitis suppurativa symptoms in females.
11 citations,
October 2021 in “Journal of The European Academy of Dermatology and Venereology” 1 citations,
September 2021 in “Pharmaceutics” 2 citations,
July 2021 in “The Journal of Sexual Medicine” 
17 citations,
June 2021 in “Journal of Endocrinological Investigation” Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.
January 2021 in “Translational Andrology and Urology” 
40 citations,
January 2021 in “JAMA Dermatology” Finasteride may cause suicidal thoughts and mental side effects, especially in young people with hair loss.
30 citations,
October 2020 in “Nature Communications” Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
15 citations,
May 2020 in “Anais Brasileiros De Dermatologia” Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.
32 citations,
March 2020 in “Drug Design Development and Therapy” Finasteride shows promise for female hair loss, but more research needed.
6 citations,
January 2020 in “Dermatology” Finasteride may increase suicide risk; more research needed.
17 citations,
January 2020 in “The World Journal of Men's Health” The document highlighted significant health risks associated with long-term use of finasteride and dutasteride, commonly prescribed for benign prostatic hyperplasia (BPH) and androgenetic alopecia (AGA). These drugs induced a novel form of androgen deficiency, leading to various metabolic dysfunctions such as non-alcoholic fatty liver disease (NAFLD), insulin resistance (IR), type 2 diabetes mellitus (T2DM), dry eye disease, and potential kidney dysfunction. Studies in both animal models and human subjects indicated liver lipid accumulation, impaired glucose disposal, and increased risk of T2DM. A cohort study of 230 men treated with dutasteride for 36-42 months showed increased blood glucose, cholesterol levels, and liver enzyme activities. The review called for heightened awareness of these potential adverse effects and reconsideration of prolonged use of these medications.
3 citations,
January 2020 in “Skin appendage disorders” In Spain, dermatologists most commonly prescribe topical minoxidil and oral finasteride for male hair loss, and topical minoxidil and oral contraceptives for female hair loss. The use of oral dutasteride and oral minoxidil has significantly increased over the past three years.
30 citations,
January 2020 in “Fertility and Sterility” 
15 citations,
July 2019 in “Journal of Biological Inorganic Chemistry” Finasteride helps prevent kidney stones, but side effects need more research.
18 citations,
July 2019 in “Journal of The European Academy of Dermatology and Venereology” Finasteride use doesn't cause sexual dysfunction in men with hair loss.
10 citations,
May 2019 in “International Journal of Environmental Research and Public Health” Finasteride may cause kidney damage.
29 citations,
April 2019 in “BMJ. British medical journal” Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.
8 citations,
September 2018 in “Current Sexual Health Reports” Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.
40 citations,
April 2018 in “Endocrine” PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.
178 citations,
July 2017 in “Journal of The American Academy of Dermatology” Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.
50 citations,
March 2017 in “PeerJ” Using finasteride or dutasteride may cause long-lasting erectile dysfunction.
2 citations,
December 2016 in “Andrology” 
69 citations,
July 2015 in “Pharmacotherapy” Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.
81 citations,
May 2015 in “American Journal of Men's Health” Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.
73 citations,
October 2013 in “The Journal of Sexual Medicine” Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.
1 citations,
January 2012 in “Human health handbooks” 
75 citations,
December 2011 in “British Journal of Dermatology” Female pattern hair loss can be treated with medications, surgery, and cosmetic products, considering its psychological impact.
239 citations,
November 2000 in “Journal of The American Academy of Dermatology” Finasteride doesn't effectively treat hair loss in postmenopausal women.
416 citations,
September 1997 in “Journal of Investigative Dermatology” People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.
