A Community-Oriented Survey on the Association Between Androgenetic Alopecia and Metabolic Syndrome in Chinese People

November 2022 in “ Frontiers in Medicine ”

Hongliu Zhu, Haijian Guo, Yihong Gao, Yuegang Wei, Tao Mao, Jianqiu Yang

androgenetic alopecia metabolic syndrome hypertension dyslipidemia waist circumference hip circumference waist-hip ratio hyperuricemia AGA

TLDR Severe hair loss in Chinese men is linked to high blood pressure, while in women, it's linked to larger waist size and cholesterol issues.

This study involving 3,703 Chinese participants (1,414 men and 2,289 women) found that severe androgenetic alopecia (AGA) in males is significantly associated with higher risks of hypertension, while in females, AGA is linked to increased waist circumference, hip circumference, waist-hip ratio, and dyslipidemia. Logistic regression analysis identified hypertension as a significant factor affecting AGA in males, and dyslipidemia, waist circumference, and hyperuricemia as significant factors in females. The study highlights a potential link between AGA and components of metabolic syndrome, with notable gender differences.

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Research cited in this study

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research Systematic Review and Meta-Analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia

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People with androgenetic alopecia have a higher risk of metabolic syndrome.

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Men with hair loss have higher BMI, waist size, blood pressure, and are linked to smoking and inactivity.

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No clear link between hair loss and metabolic syndrome, but some differences in blood pressure and glucose levels.

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59 citations, May 2014 in “Expert Opinion on Therapeutic Targets”

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

research Androgenetic Alopecia and Cardiovascular Risk Factors in Men and Women: A Comparative Study

110 citations, July 2010 in “Journal of The American Academy of Dermatology”

Hair loss linked to higher heart disease risk in both men and women.

research Prevalence of Androgenetic Alopecia in China: A Community-Based Study in Six Cities

126 citations, January 2010 in “British Journal of Dermatology”

Baldness is more common in Chinese men than women, increasing with age, and is influenced by genetics.

research Hypertension and Aldosterone Levels in Women with Early-Onset Androgenetic Alopecia

45 citations, November 2009 in “British Journal of Dermatology”

Women with early hair loss have higher blood pressure and aldosterone; screening and treatment may help.

research Male Pattern Baldness: Current Treatments, Future Prospects

40 citations, July 2008 in “Drug Discovery Today”

Current treatments for male pattern baldness include minoxidil and finasteride, with new options being developed.

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6 / 1000+ results

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 864 upvotes 4 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 6 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Anyone else growing tired of the finasteride wars?

in Finasteride/Dutasteride 169 upvotes 1 year ago

The conversation is about differing experiences with finasteride for hair loss, with some users reporting side effects and others not, and the debate over the drug's safety and effectiveness. Specific treatments mentioned include finasteride, dutasteride, and topical finasteride.

community Do we have to be junkies? That's funny

in Research/Science 13 upvotes 7 months ago

The conversation discusses using finasteride, dutasteride, minoxidil, cialis, and metformin to protect hair and health. Some users caution against self-prescribing these drugs due to potential risks and complications.

community Being Safe on Oral Minoxidil: tl;dr on the literature.

in Research/Science 49 upvotes 1 month ago

Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

community It’s over. NOTHING has worked.

in Chat 95 upvotes 2 years ago

A user who has been trying various treatments for hair loss for four years, with no success. Suggestions include use of minoxidil, finasteride, RU58841, microneedling, supplements and multivitamins, lifestyle changes, scalp biopsy, and SMP.

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