Case Report: A Study of the Clinical Characteristics and Genetic Variants of Post-Finasteride Syndrome Patients

    September 2022 in “ Translational Andrology and Urology ”
    Xiaogang Li, Ye Guo, Yi Lu … Yongzhe Li
    Studysummary This study found that in young men with post-finasteride syndrome, there are potential genetic risk factors associated with psychological and sexual dysfunctions, suggesting genetic screening may be beneficial before prescribing finasteride.
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    Research cited in this study 15

    1. Disproportional Signal of Sexual Dysfunction Reports Associated with Finasteride Use in Young Men with Androgenetic Alopecia: A Pharmacovigilance Analysis of VigiBase Journal of The American Academy of Dermatology · 2022
    2. Topical Finasteride for Male and Female Pattern Hair Loss: Is It a Safe and Effective Alternative? Journal of Cosmetic Dermatology · 2022
    3. 5-Alpha Reductase Inhibitor Related Litigation: A Legal Database Review International Journal of Andrology · 2021
    4. Further Studies of Effects of Finasteride on Mood and Suicidal Risk Journal of Clinical Psychopharmacology · 2021
    5. Sexual, Physical, And Overall Adverse Effects In Patients Treated With 5α-Reductase Inhibitors: A Systematic Review And Meta-Analysis Asian Journal of Andrology · 2021
    6. The Connection of 5-Alpha Reductase Inhibitors to the Development of Depression Biomedicine & Pharmacotherapy · 2021
    7. Finasteride for Hair Loss: A Review Journal of Dermatological Treatment · 2021
    8. Risk of Depression Associated with Finasteride Treatment Journal of Clinical Psychopharmacology · 2021
    9. Association Between 5-Alpha Reductase Inhibitor Use and the Risk of Depression: A Meta-Analysis Urology Journal · 2020
    10. Post-Finasteride Syndrome: An Emerging Clinical Problem Neurobiology of Stress · 2019
    11. Persistent Erectile Dysfunction After Discontinuation of 5-Alpha Reductase Inhibitor Therapy in Rats Depending on the Duration of Treatment The World Journal of Men s Health · 2018
    12. Why Odds Ratios Can Be Tricky Statistics The Journal of Clinical Psychiatry · 2018
    13. Neuroactive Steroid Levels and Psychiatric and Andrological Features in Post-Finasteride Patients The Journal of Steroid Biochemistry and Molecular Biology · 2017
    14. Investigation of the Plausibility of 5-Alpha-Reductase Inhibitor Syndrome Skin appendage disorders · 2016
    15. Effects of 5-Alpha Reductase Inhibitors on Erectile Function, Sexual Desire, and Ejaculation Expert Opinion on Drug Safety · 2012

    Related research 3

    1. Literature Review: Population-Based Studies Using the Clinical Practice Research Datalink to Assess the Risk of Erectile Dysfunction Associated with the Use of 5-α Reductase Inhibitors Hair transplant forum international · 2019
    2. Finasteride and Erectile Dysfunction in Patients with Benign Prostatic Hyperplasia or Male Androgenetic Alopecia The World Journal of Men's Health · 2018
    3. Persistent Sexual Side Effects of Finasteride: Could They Be Permanent? The Journal of Sexual Medicine · 2012