28 citations
,
August 2011 in “Journal of The American Academy of Dermatology” This study found that men with early-onset androgenetic alopecia had significantly larger prostate volumes and lower urinary flow rates compared to healthy controls, suggesting a possible link between AGA and prostate-related urinary symptoms.
36 citations
,
April 2011 in “Journal of The American Academy of Dermatology” People with hair loss have higher risk of high blood sugar and diabetes, and lower levels of a specific hormone.
235 citations
,
January 2011 in “Journal of Clinical Investigation” This study found that androgenetic alopecia may involve a defect in the conversion of hair follicle stem cells to progenitor cells, as demonstrated by a reduced presence of progenitor cells in bald scalp samples.
122 citations
,
November 2010 in “Journal of Dermatological Science” This study found that increased expression of type II 5α-reductase, androgen receptors, and Hic-5/ARA55 in dermal papilla cells upregulates androgen sensitivity, playing a key role in androgenetic alopecia pathogenesis.
15 citations
,
October 2010 in “International Journal of Dermatology” Women with AGA have higher lipid levels, increasing heart disease risk.
9 citations
,
September 2010 in “Dermatologic Therapy” This article concludes that finasteride is a safe treatment for androgenetic alopecia and does not increase the risk of high-grade prostate cancer, despite past concerns from the Prostate Cancer Prevention Trial.
151 citations
,
August 2010 in “British Journal of Dermatology” This guideline reviews the diagnosis of androgenetic alopecia and offers expert consensus recommendations tailored to males, females, and adolescents, but reports no new clinical results.
110 citations
,
July 2010 in “Journal of The American Academy of Dermatology” Hair loss linked to higher heart disease risk in both men and women.
15 citations
,
May 2010 in “Actas Dermo-Sifiliográficas” This study found that men with early-onset androgenetic alopecia had a higher prevalence of metabolic syndrome and carotid atheromatous plaques than control subjects, suggesting a need for cardiovascular screening in this group.
100 citations
,
April 2010 in “Expert Opinion on Pharmacotherapy” This article reviews existing treatments for male-pattern hair loss, noting that while they can slow progression, they generally achieve only partial hair regrowth.
23 citations
,
March 2010 in “Actas Dermo-Sifiliográficas” In this study, early-onset androgenetic alopecia in men was associated with a higher prevalence of metabolic syndrome and carotid atherosclerosis compared to controls, suggesting cardiovascular screening might be beneficial for this group.
53 citations
,
March 2010 in “British Journal of Dermatology” This study found that androgenetic alopecia is the leading cause of hair loss in adolescents and may indicate endocrine disorders, emphasizing the need for accurate diagnosis.
126 citations
,
January 2010 in “British Journal of Dermatology” This study found that the prevalence of androgenetic alopecia in Chinese men and women was lower than in Caucasians and similar to that in Koreans.
37 citations
,
January 2010 in “Acta dermato-venereologica” This study found that both men and women with androgenic alopecia had significantly higher triglycerides, total cholesterol, and LDL-C and lower HDL-C levels than controls, suggesting increased dyslipidemia prevalence.
24 citations
,
January 2010 in “Endocrine Regulations” In this study, men taking 1 mg/day of finasteride for 12 months showed minor metabolic changes and slight improvements in glucose metabolism.
45 citations
,
November 2009 in “British Journal of Dermatology” This study found that women with early-onset androgenetic alopecia had higher aldosterone levels and blood pressure, suggesting a possible link to the increased prevalence of hypertension in this group.
21 citations
,
October 2009 in “Molecular Biology Reports” 
30 citations
,
June 2009 in “British Journal of Dermatology” This study suggests that elevated aldosterone may contribute to androgenic alopecia development and its association with higher hypertension prevalence, emphasizing the importance of blood pressure screening in affected patients.
42 citations
,
April 2009 in “Human Genetics” This study suggests that the AGA risk haplotype in Europeans was driven to high frequency by positive selection, likely associated with a variant in the EDA2R gene.
212 citations
,
September 2008 in “Journal of The American Academy of Dermatology” This review discusses the various treatment options for male and female pattern hair loss and provides no new clinical results; the authors outline the most effective strategies based on existing evidence.
18 citations
,
March 2008 in “British Journal of Dermatology” This study found that finasteride 1 mg daily decreased 5alpha-dihydrotestosterone levels and improved hair growth in younger men with androgenetic alopecia, with higher initial hormone levels predicting better response.
125 citations
,
May 2007 in “Journal of The American Academy of Dermatology” This study describes the development of the BASP classification system, providing a universal and systematic approach for classifying pattern hair loss in both men and women.
203 citations
,
December 2004 in “Journal of The American Academy of Dermatology” This article reviews the historical developments in understanding and treating male pattern hair loss, emphasizing the role of dihydrotestosterone and 5α-reductase inhibitors, but reports no new clinical findings.
131 citations
,
August 2000 in “International Journal of Dermatology” Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
