Elevated Aldosterone Levels in Patients with Androgenetic Alopecia

    Salvador Arias-Santiago, M.T. Gutiérrez-Salmerón, Luisa Castellote-Caballero, Ramón Naranjo-Sintes
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    TLDR Higher aldosterone levels link to hair loss and high blood pressure.
    This study examined the relationship between androgenetic alopecia (AGA) and hypertension, finding that patients with AGA had significantly higher systolic blood pressure values and aldosterone levels than healthy controls. They also found that those with hypertension had higher aldosterone levels than those without, suggesting that elevated aldosterone levels may contribute to both hypertension and the development of AGA. The authors suggest that screening for high blood pressure in people with AGA could lead to earlier diagnosis and initiation of appropriate treatment.
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      in Research/Science  17 upvotes 1 week ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

      community Being Safe on Oral Minoxidil: tl;dr on the literature.

      in Research/Science  50 upvotes 11 months ago
      Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

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