How Our Microbiome Influences the Pathogenesis of Alopecia Areata

    October 2022 in “ Genes
    Pedro Sánchez-Pellicer, Laura Navarro-Moratalla, Eva Núñez‐Delegido, Juan Agüera-Santos, Vicente Navarro-López
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    TLDR Our microbiome may affect the development of the hair loss condition Alopecia Areata, but more research is needed to understand this relationship.
    The document "How Our Microbiome Influences the Pathogenesis of Alopecia Areata" reviews the role of the microbiome in the development of Alopecia Areata (AA), an autoimmune hair loss condition. It highlights that AA is influenced by genetic predisposition, immune system factors, and lifestyle factors such as sleep quality and obesity. The document discusses the role of the hair follicle and scalp microbiota in AA, with studies showing alterations in the scalp microbiota of AA patients. It also explores the potential role of gut microbiota in AA, with some studies indicating changes in gut microbiota in AA patients. However, the exact role of the microbiome in AA is not fully understood, and further research is needed. The document also suggests the potential of therapeutic manipulation of the microbiome as a treatment for AA.
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