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Glossary Gut Microbiota

diverse community of microorganisms in the digestive tract

Gut microbiota, also known as gut flora or intestinal microbiota, refers to the diverse community of microorganisms, including bacteria, viruses, fungi, and other microbes, that inhabit the digestive tracts of humans and other animals. These microorganisms play a crucial role in digestion, immune function, and overall health by breaking down complex carbohydrates, synthesizing vitamins, and protecting against harmful pathogens.

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research Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition

37 citations , September 2018 in “Psychoneuroendocrinology”

This study found that finasteride treatment in male rats led to enduring effects on depressive-like behavior, hippocampal neurogenesis and neuroinflammation, and gut microbiota composition after withdrawal.

research LC-APCI+-MS/MS method for the analysis of ten hormones and two endocannabinoids in plasma and hair from the mice with different gut microbiota

18 citations , February 2020 in “Journal of pharmaceutical and biomedical analysis”

This study using high-performance liquid chromatography reported that mice with more diverse gut microbiota had higher levels of specific compounds in hair compared to those with less diversity, with stress affecting certain plasma levels.

research Alterations of gut microbiota composition in post-finasteride patients: a pilot study

17 citations , September 2020 in “Journal of Endocrinological Investigation”

This study found that the gut microbiota composition in patients with post-finasteride syndrome differs significantly from healthy controls, with reduced diversity and specific microbial changes, suggesting a potential diagnostic marker and therapeutic target.

research Implication of Human Bacterial Gut Microbiota on Immune-Mediated and Autoimmune Dermatological Diseases and Their Comorbidities: A Narrative Review

16 citations , January 2021 in “Dermatology and therapy”

This review discusses the role of gut microbiota in autoimmune and immune-mediated dermatological conditions like lupus and psoriasis, but reports no new clinical results; the authors emphasize the need for further study into microbial signatures and treatments.

research Gut microbiota in alopecia areata

13 citations , January 2022 in “Advances in Dermatology and Allergology”

This review discusses the relationship between gut microbiota and alopecia areata, and it does not report new clinical results.

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community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 1 year ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community Gut microbiome imbalances linked to scalp inflammation and hair follicle impact

in Technology 243 upvotes 4 months ago

Gut microbiome imbalances can cause scalp inflammation and affect hair follicles, potentially leading to hair loss. Treatments include finasteride, peptides like BPC-157, TB-500, KPV, and lifestyle changes such as diet and exercise.

community What if DHT is not the vilan.

13 upvotes 5 years ago

Hair loss may be influenced more by inflammation, microbiome imbalances, and gut health than DHT. Treatments discussed include minoxidil, finasteride, RU58841, fecal microbiota transplants, and JAK inhibitors.

community Another theory for hair loss: Parasites in gut.

in Research/Science 9 months ago

Parasites in the gut may contribute to hair loss by depleting essential nutrients and disrupting hormone balance. An imbalance of hormones, not just DHT, could be a factor in androgenic alopecia.

community I was a non-responder to Minoxidil before my esophagus surgery

in Research/Science 38 upvotes 2 years ago

The user experienced improved hair density after switching from 5mg to 2.5mg oral Minoxidil post-esophagus surgery, suggesting a possible link between gut health and hair growth. They theorize that long-term medication may have blocked nutrient intake, affecting hair regrowth.

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