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GlossaryGlucagon-Like Peptide-1

hormone that regulates blood sugar and promotes fullness

Glucagon-Like Peptide-1 (GLP-1) is a hormone produced in the gut that plays a crucial role in regulating blood sugar levels by enhancing insulin secretion and inhibiting glucagon release after eating. It also slows gastric emptying and promotes a feeling of fullness, making it a target for treatments in type 2 diabetes and obesity.

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research Glucagon-Like Peptide-1 Receptor and Proglucagon Expression in Mouse Skin

37 citations, March 2006 in “Regulatory Peptides”

Mice skin has components that could help with hair growth and might be used for diabetes treatment.

research Risk of Alopecia Areata with Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss

February 2025 in “medRxiv (Cold Spring Harbor Laboratory)”

GLP-1 agonists may increase the risk of hair loss.

research Exploring the Hair Loss Risk in Glucagon-Like Peptide-1 Agonists: Emerging Concerns and Clinical Implications

January 2025 in “Journal of the European Academy of Dermatology and Venereology”

Newer GLP-1 drugs like semaglutide may cause hair loss.

Risk of Suicide, Hair Loss, and Aspiration with Glucagon-Like Peptide 1 Receptor Agonists: A Real-World Pharmacovigilance Study from the FAERS Database

research Risk of Suicide, Hair Loss, and Aspiration with Glucagon-Like Peptide 1 Receptor Agonists: A Real-World Pharmacovigilance Study from the FAERS Database

November 2024 in “Circulation”

GLP1-RAs may have higher reports of suicide and hair loss, but no strong evidence links them to these issues.

A 12-Week Treatment with the Long-Acting Glucagon-Like Peptide 1 Receptor Agonist Liraglutide Leads to Significant Weight Loss in a Subset of Obese Women with Newly Diagnosed Polycystic Ovary Syndrome

research A 12-Week Treatment with the Long-Acting Glucagon-Like Peptide 1 Receptor Agonist Liraglutide Leads to Significant Weight Loss in a Subset of Obese Women with Newly Diagnosed Polycystic Ovary Syndrome

61 citations, January 2015 in “Hormones”

Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.

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community Gyno & testoterone level

in Finasteride 282 upvotes 9 months ago

Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.