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GlossaryGlucagon-Like Peptide-1

hormone that regulates blood sugar and promotes fullness

Glucagon-Like Peptide-1 (GLP-1) is a hormone produced in the gut that plays a crucial role in regulating blood sugar levels by enhancing insulin secretion and inhibiting glucagon release after eating. It also slows gastric emptying and promotes a feeling of fullness, making it a target for treatments in type 2 diabetes and obesity.

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research Glucagon-Like Peptide-1 Receptor and Proglucagon Expression in Mouse Skin

37 citations , March 2006 in “Regulatory Peptides”

Mice skin has components that could help with hair growth and might be used for diabetes treatment.

research Use of Glucagon-Like Peptide-1 Agonists in Modulating Preexisting Dermatologic Disease: A Systematic Review

September 2025 in “Cureus”

GLP-1 agonists may help treat certain skin conditions.

research Hair Loss Associated With Glucagon-Like Peptide-1 Receptor Agonist Use: A Systematic Review

September 2025 in “Cureus”

GLP-1 receptor agonists may cause hair loss, but more research is needed.

research Alopecia as an Emerging Adverse Effect Associated with Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss: A Scoping Review

August 2025 in “Cureus”

GLP-1 receptor agonists for weight loss may cause hair loss, especially in women.

research Risk of Alopecia Areata with Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss

February 2025 in “medRxiv (Cold Spring Harbor Laboratory)”

GLP-1 agonists may increase the risk of hair loss.

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community Any treatments in development that could theoretically give complete regrowth?

in Research/Science 8 upvotes 9 months ago

New hair loss treatments like PP-405, AMP-303, and SCUBE3 are being discussed, but none are confirmed to fully restore hairlines. Current treatments like Minoxidil, Finasteride, and RU58841 are still widely used, with some hope for future advancements in hair regrowth.

community Will Pp405 be the Ozempic of bald Guys

in Research/Science 104 upvotes 1 week ago

PP405 is being discussed as a potential hair loss treatment, possibly more effective than minoxidil. There are concerns about its effectiveness and product contamination, but some users report early signs of hair regrowth.

community Gyno & testoterone level

in Finasteride 282 upvotes 1 year ago

Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.