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    Glossary Dipeptidyl Peptidase-4 Inhibitors

    block the enzyme DPP-4 to help regulate blood sugar

    Dipeptidyl Peptidase-4 Inhibitors, often abbreviated as DPP-4 inhibitors, are a class of oral medications used to manage type 2 diabetes. They work by blocking the enzyme DPP-4, which results in increased levels of incretin hormones. These hormones help to regulate blood sugar by increasing insulin release and decreasing glucagon levels, particularly after meals.

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    Research 10 of 238

    1. 557 A peptide derivative with known anti-wrinkle properties was identified as potent dipeptiylpeptidase-4 inhibitor Journal of Investigative Dermatology · 2016
    2. Inhibiting dipeptidyl peptidase 4 positive fibroblasts using zinc sulfide cellulose nanofiber scaffolds to achieve scarless healing International Journal of Biological Macromolecules · 2024 · 4 citations
    3. 973 Dipeptidyl-peptidase 4 (DPP4)-positive fibroblasts are responsible for secretion of pro-fibrotic matrix proteins in the human skin Journal of Investigative Dermatology · 2019
    4. Linagliptin-Associated Alopecia and Bullous Pemphigoid European Journal of Case Reports in Internal Medicine · 2019 · 7 citations
    5. Cardiovascular profile of pharmacological agents used for the management of polycystic ovary syndrome Therapeutic Advances in Endocrinology and Metabolism · 2019 · 4 citations
    6. 613 Bacteria induce skin regeneration via IL-1β signaling Journal of Investigative Dermatology · 2021
    7. 612 Wnt signaling induces fibrotic fat loss via DPP4 in skin fibrosis Journal of Investigative Dermatology · 2021
    8. Alopecia areata universalis nach Sitagliptin-Einnahme ˜Derœ Hautarzt · 2020 · 2 citations
    9. Repurposing DPP4-Inhibition to Improve Hair Follicle Activation and Regeneration Journal of Investigative Dermatology · 2023
    10. Mimosine Dipeptide Enantiomsers: Improved Inhibitors against Melanogenesis and Cyclooxygenase Molecules · 2015 · 25 citations
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